Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE2
60 participants
INTERVENTIONAL
2024-11-07
2025-05-08
Brief Summary
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Detailed Description
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patients diagnosed with symptomatic irreversible pulpitis with symptomatic apical periodontitis.
patients will be asked to rate their pre treatment pain on visual analogue scale from 0-10
patients with pain score \<8 will be considered
Anesthesia and isolation : after administration of local anesthesia , rubber dam application will be done
Acess cavity : acess will be gained with round bur using air turbune handpiece with copious water cooling
Working length : a size 10k file will be inserted into the canal to determine the working length with the help of radiograph
Cleaning and shaping : Extirpation of pulp will be done followed by canal preparation with manual and endodontic motor using naocl and EDTA .
final irrigation will be performed using 17% EDTA and 5.25% NaOCl
Patients will be divided into 2 group in control group : final irrigation will be done using 5ml of saline at room temperature in cold group : final irrigation will be done using 5ml of cold saline at 2.5°C
the solution will be stored in the refrigerator until use irrigation will be performed for 5 min in both groups using 27 G beveled needle tip inserted 2mm short of WL.
Obturation ; In both groups , canals will be dried with paper points and obturated using gutta percha cones with zinc oxide eugenol sealer
Restoration : acces cavity will be restroed with direct composite restoration or high viscosity glass ionomer cement
each patient will be given instruction to acess the post operative pain .
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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normal saline group
In control group , canals will be irrigated with 5ml of normal saline at room temperature
Irrigation Solution
normal saline will be used as irrigation solution
cryotherapy (cold saline group)
in cold saline group , canals will be irrigated with 5 ml of cold saline at a temperature of 2.5° C
Irrigation Solution
normal saline will be used as irrigation solution
Interventions
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Irrigation Solution
normal saline will be used as irrigation solution
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* maxillary or mandibular single rooted teeth
* systemically healthy patients
* patients having pain score \< 8
Exclusion Criteria
* teeth with calcified canals and previously treated teeth
* tooth with immature apices or resorption
* patients allergic to local anesthesia
* pregnant or lactating mothers
* patients who are immunocompromised .
20 Years
40 Years
ALL
Yes
Sponsors
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Armed Forces Institute of Dentistry, Pakistan
OTHER
Responsible Party
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Hira Amjad
Dr. Hira Amjad , Principal investigator and Resident Operative Dentistry and Endodontics
Principal Investigators
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Hira Amjad, BDS
Role: PRINCIPAL_INVESTIGATOR
Armed Forces Institude Of Dentistry
Locations
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Armed Forces Institute of Dentistry
Rawalpindi, Punjab Province, Pakistan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Cryotherapy
Identifier Type: -
Identifier Source: org_study_id
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