Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment

NCT ID: NCT07062419

Last Updated: 2025-10-01

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 58 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-01-01
• Study Completion Date: 2025-08-30

Brief Summary

Fifty-eight patients aged 18-60 years, diagnosed with symptomatic or asymptomatic apical periodontitis will be randomly allocated into two groups: Group A (EndoActivator) and Group B (conventional syringe irrigation). preoperative pain will be evaluated in all patients requiring root canal treatment using visual analogue scale before initiating the procedure.

Postoperative pain will be measured using the Visual Analog Scale (VAS) at 24, 36, 48 hours and one week.

Detailed Description

This randomized clinical study will evaluate the effect of two different irrigation techniques on postoperative pain following root canal treatment in patients with apical periodontitis. A total of 58 patients will be randomly assigned to one of two groups: one group will receive irrigation using the EndoActivator system, while the other group undergo conventional syringe irrigation. The objective is to determine whether the irrigation technique influences the level of postoperative discomfort experienced by patients. Pain levels will be assessed at specific time intervals to track the pattern of recovery and provide insight into the clinical effectiveness of each method in terms of patient comfort.

Conditions

Post Operative Pain; Root Canal Therapy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

one group will receive irrigation during root canal treatment will be activated by an Endoactivator

activation of an irrigant by using certain ultrasonic frequency to enhance antimicrobial action of irrigant

Group Type: EXPERIMENTAL

endoactivator

Intervention Type: DEVICE

activation of irrigant during root canal treatment

One group will receive irrigation during root canal treatment in which activation will not occur

This group consists of patients who will receive irrigation during root canal treatment using the conventional syringe irrigation technique without the use of the EndoActivator system.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

endoactivator

activation of irrigant during root canal treatment

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• irreversible pulpitis
• symptomatic apical periodontitis
• asymptomatic apical periodontitis
• compliant patients
• sufficient ferrule for post operative restoration

Exclusion Criteria

• periapical abcess
• severe periodontal disease with guarded periodontal prognosis
• teeth with guarded post operative restoration prognosis
• non compliant patients

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

CMH Lahore Medical College and Institute of Dentistry

OTHER

Sponsor Role: lead

Responsible Party

Samia Rasool

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Imran Khan, BDS FCPS

Role: STUDY_DIRECTOR

28 military dental centre

Locations

28 Military Dental Centre

Lahore, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

107/Civ/Trg/Op/15/24

Identifier Type: -

Identifier Source: org_study_id