Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods
NCT ID: NCT07196215
Last Updated: 2025-09-29
Study Results
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Basic Information
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NOT_YET_RECRUITING
NA
72 participants
INTERVENTIONAL
2026-01-01
2027-01-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Passive ultrasonic activation
passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21/25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five.
passive ultrasonic activation
passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21/25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five
Sonic activation
In group B, root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25/04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation
sonic activation
root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25/04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation
Interventions
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passive ultrasonic activation
passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21/25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five
sonic activation
root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25/04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation
Eligibility Criteria
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Inclusion Criteria
* Age range is between 20 to 50 years.
* Patients diagnosed with symptomatic irreversible pulpitis in maxillary incisor teeth.
* Patients who can understand VAS.
* Patients who give verbal consent to participate voluntarily in the study.
Exclusion Criteria
* Pregnant / lactating females (As per medical record/verbally)
* Patients who had taken preoperative drugs as anti-inflammatory analgesic or antibiotics.
* Patients with swelling or acute peri-apical abscess.
* Tooth not suitable for restoration.
* Periodontally compromised teeth.
* Retreatment cases.
20 Years
50 Years
ALL
Yes
Sponsors
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RANA AHMAD
OTHER
Responsible Party
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RANA AHMAD
Assistant Professor
References
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Gundogar M, Sezgin GP, Kaplan SS, Ozyurek H, Uslu G, Ozyurek T. Postoperative pain after different irrigation activation techniques: a randomized, clinical trial. Odontology. 2021 Apr;109(2):385-392. doi: 10.1007/s10266-020-00553-5. Epub 2020 Sep 11.
Narla RK, J RK, Pavuluri TC, P KC, Penumaka R, Nagelli RK. Effect of Different Irrigant Activation Techniques on the Penetration of Calcium Hydroxide, an Intracanal Medicament: An In Vitro Study. Cureus. 2023 Nov 13;15(11):e48768. doi: 10.7759/cureus.48768. eCollection 2023 Nov.
7. Nivedhitha S. Influence of different irrigant activation techniques in post-operative endodontic pain-a review of literature. Int J Dentistry Oral Sci. 2021;8(5):2659-65.
6. Abou Khalaf Y, Hashem A, Kamel W, Badr M. Postoperative pain after different root canal irrigant activation methods; (randomized clinical trial). Future Dent J. 2021;7(1):1-6.
5. Elzainy P, Hussein W, Hashem A, Badr M. Post-operative pain after different root canal irrigant activation methods in patients with acute apical periodontitis (Randomized Clinical Trial). Open Access Maced J Med Sci. 2022;10(D):331-7.
Kumar P, Yadav SK, Chugh VK, Sharma R, Pathak K, Duraisamy A. Comparative Assessment of Postoperative Pain After Three Irrigation Techniques in Single-Rooted Teeth With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis: A Randomized Controlled Trial. Cureus. 2024 Jul 29;16(7):e65618. doi: 10.7759/cureus.65618. eCollection 2024 Jul.
3. Salim A, Darrag A, Ghoneim W. Post-operative pain after single-visit endodontic treatment using different root canal irrigation activating techniques. Egypt Dent J. 2021;67(4):3719-30.
Sathorn C, Parashos P, Messer H. The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review. Int Endod J. 2008 Feb;41(2):91-9. doi: 10.1111/j.1365-2591.2007.01316.x. Epub 2007 Oct 23.
Parirokh M, Jalali S, Haghdoost AA, Abbott PV. Comparison of the effect of various irrigants on apically extruded debris after root canal preparation. J Endod. 2012 Feb;38(2):196-9. doi: 10.1016/j.joen.2011.10.027. Epub 2011 Dec 6.
Other Identifiers
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TUF/IRB/21/25
Identifier Type: -
Identifier Source: org_study_id
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