Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.

NCT ID: NCT03448263

Last Updated: 2018-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

216 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-04

Study Completion Date

2018-02-06

Brief Summary

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The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used. Methodology: All 216 patients had upper or lower molar, premolar or anterior teeth selected for conventional RCT for prosthetic reasons detected with only vital pulps. Of the sample of 216 teeth, were selected to the 3 instrumentation methods. For hand instrumentation, Balanced Force were used. All canals were clean and shaped with hand Flex-R files (fMoyco/Union Broach, York PA, USA). For mechanical shaping, all instruments were used with a micro motor (VDW, Munich Germany). WaveOne and Reciproc instruments. Final irrigation with cold (6oC) 17% EDTA served as a lubricant.

Detailed Description

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Patient selection Two hundred and sixteen of 245 patients (119 women and 97 men) aged 18-65 years were incorporated in this research while 29 were excluded as not meeting the inclusion criteria. (Fig. 1). Sample size estimate was achieved according with a method for this specific purpose (Cochran's method, 1986). Therefore, the 56 teeth allocated to each group were adequate to confirm an essential sample size.

For hand instrumentation, the Balanced Force technique was used. All root canals were shaped with hand Flex-R files (Moyco/Union Broach, York PA, USA). Gates-Glidden drills (Dentsply Maillefer) sizes #2 and #3 were used at the orifice of the root canals. For mechanical preparations, all instruments were used with a micro motor (VDW Silver Motor, VDW, Munich Germany). Torque and rotation were preset for each Reciproc or WaveOne instrument. Rotary Ni-Ti instruments were used in continuous brushing rotary motion and reciprocating mode respectively.

Dentinal debris was eliminated from the file with a gauze, instantaneously to the instrument change (WaveOne) or after 2-3 in-and-out (pecking) movements (Reciproc) following the manufacturers' recommendations. Each root canal was irrigated with 2.5mL 2.6% NaOCl. Irrigation was performed using a 24-gauge needle (Max-I-Probe; Tulsa Dental, York, PA) and a 31-G NaviTip needle (Ultradent Products Inc, South Jordan, UT) when reaching the WL after each instrument insertion.

Group BF. For the Balanced Force group, the root canals were shaped and shaped using a #40 instrument for thin or curved canals and a #55 file for wide canals.

Group WON. For the WaveOne group, a file size 25/.08 was used to prepare narrow, straight and curved canals, and a file size 40/.08 was used for large and wide canals.

Three in-and-out pecking motions were used with an amplitude of not more than 3 mm until reaching the estimated working length.

Group REC. The R25 (size 25/ .08) instrument was used in thin and curved root canals, and R40 files (40/ .06) were used in wide root canals. Three in-and-out pecking motions were used with an amplitude of not more than 3 mm until reaching the estimated working length.

Conditions

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Post Operative Pain

Keywords

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pain post endodontic pain root canal treatment

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Random Selection of instrumentation groups. Of the sample of 216 teeth, 72 were randomly assigned to the one of the 3 instrumentation methods. Treatment was performed by 3 experienced endodontists; each prepared 72 teeth, 24 per technique.
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Certified endodontists trained in the procedures, devices, and systems investigated took part in the research. All experts tracked a pre-established procedure for the Balanced Force technique, WaveOne, and Reciproc instrument systems.

Study Groups

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Group BF

The root canals were cleaned and shaped using a #40 instrument for thin or curved canals and a #55 file for widespread canals.

Group Type EXPERIMENTAL

Balanced Force technique

Intervention Type PROCEDURE

Flex-R files sizes 15-45 taper .02 were used according to the technique on each tooth

WaveOne technique

Intervention Type PROCEDURE

WaveOne instrument was used to prepare narrow, straight and curved canals, and file (40.08) was used for large canals.

Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Reciproc technique

Intervention Type PROCEDURE

Reciproc files were used in wide canals. Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Group WON

WaveOne files was used to prepare narrow, straight and curved canals, and a file (40.08) was used for large and wide canals.

Group Type EXPERIMENTAL

Balanced Force technique

Intervention Type PROCEDURE

Flex-R files sizes 15-45 taper .02 were used according to the technique on each tooth

WaveOne technique

Intervention Type PROCEDURE

WaveOne instrument was used to prepare narrow, straight and curved canals, and file (40.08) was used for large canals.

Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Reciproc technique

Intervention Type PROCEDURE

Reciproc files were used in wide canals. Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Reciproc instruments

Reciproc instrument was used in thin and curved RC, and R40 files (40.06) were used in wide canals.

Group Type EXPERIMENTAL

Balanced Force technique

Intervention Type PROCEDURE

Flex-R files sizes 15-45 taper .02 were used according to the technique on each tooth

WaveOne technique

Intervention Type PROCEDURE

WaveOne instrument was used to prepare narrow, straight and curved canals, and file (40.08) was used for large canals.

Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Reciproc technique

Intervention Type PROCEDURE

Reciproc files were used in wide canals. Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Interventions

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Balanced Force technique

Flex-R files sizes 15-45 taper .02 were used according to the technique on each tooth

Intervention Type PROCEDURE

WaveOne technique

WaveOne instrument was used to prepare narrow, straight and curved canals, and file (40.08) was used for large canals.

Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Intervention Type PROCEDURE

Reciproc technique

Reciproc files were used in wide canals. Three in-and-out motions were used with lengths not beyond 3 mm in the three thirds of the canal until reaching the estimated WL.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

The principal inclusion parameters were:

* absence of radiographic sign of apical periodontitis and a diagnosis of irreversible pulpitis (IP) established by affirmative response to hot and cold examinations.
* Thermal pulp examination was achieved by the corresponding author, and radiographic analysis was established by 3 certified endodontists.
* Clinical requirements were established on the next conditions: 1) The purposes and necessities of the research were spontaneously accepted. 2) Clinical Management was pointed to patients in physical and mental well-being. 3) All teeth had vital pulps and absence of apical periodontitis. 4) Positive thermal stimulation with EndoIce (Hygenic Corp, Akron, OH). 5) Teeth with enough coronal structure for rubber dam isolation. 6) No RCT done before the research. 7) No painkillers or antibiotics used 7 days' prior the clinical events started

Exclusion Criteria

Exclusion parameters were:

* the necessity for retreatment
* gravidity
* impossibility to obtain patient's approval
* patients who didn't complete inclusion necessities
* a history of medication for chronic pain or those compromising the immune response
* patients younger than 18 years and the existence of mishaps or difficulties during RCT (calcified canals, impracticality of achieving AP in any canal).
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Autonoma de Baja California

OTHER

Sponsor Role lead

Responsible Party

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Jorge Paredes Vieyra

JORGE PAREDES VIEYRA D.D.S., MsC, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Jose Clemente Orozco

Tijuana, Estado de Baja California, Mexico

Site Status

Countries

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Mexico

References

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Paredes-Vieyra J, Enriquez FJ. Success rate of single- versus two-visit root canal treatment of teeth with apical periodontitis: a randomized controlled trial. J Endod. 2012 Sep;38(9):1164-9. doi: 10.1016/j.joen.2012.05.021. Epub 2012 Jul 26.

Reference Type RESULT
PMID: 22892729 (View on PubMed)

Other Identifiers

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Endo Pain 2018

Identifier Type: -

Identifier Source: org_study_id