Measure Postoperative Pain and Bacterial Reduction After Different Final Irrigation Protocols.
NCT ID: NCT07191990
Last Updated: 2025-09-25
Study Results
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Basic Information
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ACTIVE_NOT_RECRUITING
NA
60 participants
INTERVENTIONAL
2025-07-01
2026-03-31
Brief Summary
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The aim of the study will be directed to evaluate postoperative pain and bacterial load reduction after application of different final irrigation protocols in single visit root canal treatment in patients with symptomatic irreversible pulpitis in first molar teeth. this study consists of 60 patients divided into 4 groups each group having 15 patients.
control: Final irrigation by NaOcl (2.6%) at room temperature 24 °C for 1 min interventions: I1: Final irrigation by cryotreated NaOcl (2.6%) at 2-4 °C for 1 min . I2: Final irrigation by preheated 60°C(15) NaOcl (2.6%) for 1 min. I3:Final irrigation with ultrasonic activation of NaOcl(2.6%) for 1 min
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Final irrigation by NaOcl at room temperature
Final irrigation by NaOcl (2.6%) at room temperature 24 °C for 1 min.
Final irrigation by NaOcl at room temperature
Final irrigation by NaOcl (2.6%) at room temperature 24 °C for 1 min
Final irrigation by cryotreated NaOcl.
Final irrigation by cryotreated NaOcl (2.6%) at 2-4 °C for 1 min
Final irrigation by cryotreated NaOcl.
Final irrigation by cryotreated NaOcl (2.6%) at 2-4 °C for 1 min
Final irrigation by preheated NaOcl.
Final irrigation by preheated 60°C(15) NaOcl (2.6%) for 1 min
Final irrigation by preheated NaOcl
Final irrigation by preheated 60°C(15) NaOcl (2.6%) for 1 min.
Final irrigation with ultrasonic activation of NaOcl.
Final irrigation with ultrasonic activation of NaOcl(2.6%) for 1 min
Final irrigation with ultrasonic activation of NaOcl
Final irrigation with ultrasonic activation of NaOcl(2.6%) for 1 min
Interventions
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Final irrigation by cryotreated NaOcl.
Final irrigation by cryotreated NaOcl (2.6%) at 2-4 °C for 1 min
Final irrigation by preheated NaOcl
Final irrigation by preheated 60°C(15) NaOcl (2.6%) for 1 min.
Final irrigation with ultrasonic activation of NaOcl
Final irrigation with ultrasonic activation of NaOcl(2.6%) for 1 min
Final irrigation by NaOcl at room temperature
Final irrigation by NaOcl (2.6%) at room temperature 24 °C for 1 min
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* No sex predilection.
* Patients with symptomatic irreversible pulpitis.
* Patients able to sign informed consent.
* Restorable teeth
* Positive patient's acceptance for participating in the study.
* Type III distal and mesial canal of first mandibular molar.
* Mild to moderate (5-20) ° curvature according to Schneider
Exclusion Criteria
* Medically compromised patients.
* Patients having analgesics before the treatment
* If antibiotic have been administrated during the past two weeks preoperatively.
* Patients having bruxism or clenching
* Patients having sever malocclusion associated with traumatic occlusion.
* Teeth that have:
Peri-apical periodontitis Root resorption Pain on percussion Pulp stones or calcifications Previous endodontic treatment.
-Non-patent canals
18 Years
40 Years
ALL
Yes
Sponsors
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Future University in Egypt
OTHER
Responsible Party
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Samar Tarek
principal investigator
Locations
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Future University in Egypt
Cairo, New Cairo, Egypt
Countries
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Other Identifiers
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SamarRCT01
Identifier Type: -
Identifier Source: org_study_id
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