Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling

NCT ID: NCT05419752

Last Updated: 2022-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-30

Study Completion Date

2022-08-30

Brief Summary

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aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient with necrotic teeth .

Detailed Description

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Conditions

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Necrotic Pulp Single Root Teeth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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endo sequence bioceramic sealer

obturation using Endo-sequence BC sealer

Group Type EXPERIMENTAL

bioceramic sealer

Intervention Type DRUG

bioceramic based obturating sealer

MTA fill apex calcium silicate base sealer

obturation using calcium-silicates based MTA fill-apex sealer

Group Type EXPERIMENTAL

MTA

Intervention Type DRUG

MTA based obturating sealer

AH plus resin sealer

obturation using AH Plus sealer

Group Type EXPERIMENTAL

resin sealer

Intervention Type DRUG

resin based obturating sealer

Interventions

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bioceramic sealer

bioceramic based obturating sealer

Intervention Type DRUG

MTA

MTA based obturating sealer

Intervention Type DRUG

resin sealer

resin based obturating sealer

Intervention Type DRUG

Other Intervention Names

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endosequence MTA fill apex AH Plus resin sealer

Eligibility Criteria

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Inclusion Criteria

* Patients requiring root canal treatment of single canal necrotic teeth.
* Patient from 18 to 60 years old
* Patients with Asymptomatic apical periodontitis.
* Teeth presenting with no clinical symptoms and with a periapical score from 2 to 4 according to Orstavik et al

Exclusion Criteria

* Teeth with incompletely formed apex

* Teeth requiring retreatment
* Patients having complicating systemic disease such as diabetes, malignancy, pregnancy, central nervous system disorders, Cardiovascular system disorders, respiratory disorders, asthma patients, psychiatric disorders, immunocompromised patients
* Patients taking anti-inflammatory or antibiotics
* Patients giving history of analgesic or antibiotic intake 1 week before treatment
* Patients below 18 years of age
* Patients above 65 years of age

* Patients having history of peptic ulcer or gastrointestinal bleeding
* Teeth affected with periodontal disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Elsayed Hany Elsayed Attia Elmasry

Master's degree student - faculty of dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Elsayed Hany Elmasry, bsc

Role: CONTACT

00201159536873

Other Identifiers

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ENDO 23/5/2022

Identifier Type: -

Identifier Source: org_study_id

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