Post-operative Pain Reduction

NCT ID: NCT04338633

Last Updated: 2020-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-30

Study Completion Date

2020-11-30

Brief Summary

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Recruited patients with necrotic pulp after application of conventional calcium hydroxide paste are assigned to group, Calcium hydroxide nanoparticle group and Combined Calcium hydroxide with silver nanoparticle group and record postoperative pain afterwards.

Detailed Description

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The investigator will recruit patients who are found eligible to the criteria, conventional calcium hydroxide paste , Calcium hydroxide nanoparticle and Combined Calcium hydroxide with silver nanoparticle . After 48 hours, patients will be randomly assigned to removal of intracanal medication

After the visit, patients will be asked to record post operative pain by Numerical Rating Scale)in a given sheet

Conditions

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Effects of the Elements

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
double

Study Groups

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Conventional calcium hydroxide paste

Application of Conventional calcium hydroxide paste

Group Type ACTIVE_COMPARATOR

Conventional calcium hydroxide paste

Intervention Type DRUG

Conventional calcium hydroxide paste (Ultracal) will be removed in second visit.

Calcium hydroxide nanoparticle

Application of Calcium hydroxide nanoparticle

Group Type EXPERIMENTAL

Calcium hydroxide nanoparticle

Intervention Type DRUG

Calcium hydroxide nanoparticle. manufactured in NanoTech. institute, will be removed in second visit.

Combined Calcium hydroxide with silver nanoparticle

Application of Combined Calcium hydroxide with silver nanoparticle

Group Type EXPERIMENTAL

Combined Calcium hydroxide with silver nanoparticle

Intervention Type DRUG

Combined Calcium hydroxide with silver nanoparticle will be removed in second visit.

Interventions

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Conventional calcium hydroxide paste

Conventional calcium hydroxide paste (Ultracal) will be removed in second visit.

Intervention Type DRUG

Calcium hydroxide nanoparticle

Calcium hydroxide nanoparticle. manufactured in NanoTech. institute, will be removed in second visit.

Intervention Type DRUG

Combined Calcium hydroxide with silver nanoparticle

Combined Calcium hydroxide with silver nanoparticle will be removed in second visit.

Intervention Type DRUG

Other Intervention Names

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Ultracal

Eligibility Criteria

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Inclusion Criteria

* • Medically free patients.

* Patient's age between 25-50 years.
* Sex includes both male and female.
* Radiographic evidence of a periapical radiolucent lesion associated with tooth.
* Necrotic pulp as indicated by thermal pulp testing.
* No history of previous endodontic treatment of the tooth.

Exclusion Criteria

* • Teeth with unfavorable conditions for rubber-dam application.

* Teeth with acute periapical abscesses swelling.
* Medically compromised patients.
* Immature teeth with open apices.
* Multi rooted teeth.
* Pregnant women.
Minimum Eligible Age

25 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Salah Mohamed Fahmy

PHD Candidate - Endodontic Department- Faculty of Dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Magdy Mohamed Aly, Professor

Role: STUDY_DIRECTOR

Dean of Faculty

Locations

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Faculty of Dentistry, Minia University

Minya, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mohamed Salah Hegazi

Role: CONTACT

+201224014179

Reham Hassan, Assoc Prof

Role: CONTACT

+201001542529

Facility Contacts

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Reham Hassan, Assoc Prof

Role: primary

+201001542529

References

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Singh RD, Khatter R, Bal RK, Bal CS. Intracanal medications versus placebo in reducing postoperative endodontic pain--a double-blind randomized clinical trial. Braz Dent J. 2013;24(1):25-9. doi: 10.1590/0103-6440201302039.

Reference Type BACKGROUND
PMID: 23657409 (View on PubMed)

Other Identifiers

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314

Identifier Type: -

Identifier Source: org_study_id

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