Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .

NCT ID: NCT06509295

Last Updated: 2024-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-29

Study Completion Date

2025-05-29

Brief Summary

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This study aims to assess the effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.

Detailed Description

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Conditions

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Intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Calcium Hypochlorite as root canal Irrigant on Postoperative Pain and bacterial load reduction

Treatment with Calcium Hypochlorite as root canal Irrigant

Group Type PLACEBO_COMPARATOR

Calcium Hypochlorite as Root Canal Irrigant

Intervention Type OTHER

Calcium Hypochlorite used as root canal irrigant during chemo-mechanical preparation

Sodium Hypochlorite as a root Canal Irrigant

Treatment with Sodium Hypochlorite as root canal Irrigant

Group Type ACTIVE_COMPARATOR

Calcium Hypochlorite as Root Canal Irrigant

Intervention Type OTHER

Calcium Hypochlorite used as root canal irrigant during chemo-mechanical preparation

Interventions

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Calcium Hypochlorite as Root Canal Irrigant

Calcium Hypochlorite used as root canal irrigant during chemo-mechanical preparation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Systematically healthy patient (ASA I, II).
2. Age between 20 and 55 years
3. Male or female.
4. Mandibular premolar teeth having single canals diagnosed with pulp necrosis with asymptomatic apical periodontitis.
5. Radiographic examination using Digora intraoral periapical sensor plate and software showing mandibular premolars with (0-2 mm) periapical radiolucency.

Exclusion Criteria

1. Medically compromised patients having significant systemic disorders. (ASA III or IV).
2. History of intolerance to NSAIDS.
3. Teeth with:

* Immature roots
* Vital pulp tissues.
* Association with swelling.
* Acute peri-apical abscess or acute exacerbation of a chronic abscess.
* Mobility Grade II or III.
* Previously accessed or endodontically treated
* Deep periodontal pockets more than 4 mm
* Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
4. Patients who could not interpret the NRS.
5. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women were, also, excluded.
Minimum Eligible Age

20 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Youmna Yassen

Principle investigator, resident at faculty of dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Youmna Yassen Youmna Yassen, pds

Role: CONTACT

01146877037

Other Identifiers

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ENDO 3-7-1(10/4/2024)

Identifier Type: -

Identifier Source: org_study_id

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