Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2020-11-15

Brief Summary

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In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.

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Detailed Description

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Conditions

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Acute Respiratory Failure Post Surgical (Diagnosis)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Postoperative NIV

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group N

50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery

Group Type EXPERIMENTAL

NIV

Intervention Type DEVICE

NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery

group C

50 patients recieved conventional oxygen therpy.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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NIV

NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age˃18 years, scheduled for upper abdominal surgery under general anesthesia.
* Moderate to very severe COPD (GOLD II to IV).
* ASA functional status II or greater.