Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2018-03-01
2019-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
Group V: will receive volume controlled mechanical ventilation. Group P: will receive pressure controlled mechanical ventilation.
SCREENING
SINGLE
Study Groups
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Volume controlled ventilation
Group V: Patients will receive volume controlled mechanical ventilation. (Vt 7ml/kg ideal body weight).
volume controlled ventilation
Lung ultrasound (LUS) will be performed with a 2-4 MHz phased array probe. Patients will be scanned in supine position by a recording 5 seconds videos. LUS will be assessed for the presence of B lines.
The sum of lung comets produces a score reflecting the extent of lung water accumulation. LUS will be obtained by scanning 12-rib interspaces. The sum of B-lines on each scanning site yields a score from 0 to 36
Pressure controlled ventilation
Group P: Patients will receive pressure controlled mechanical ventilation. (to achieve Vt 7 ml/kg ideal body weight, Pmax 30 cmH2O)
pressure controlled ventilation
Lung ultrasound (LUS) will be performed with a 2-4 MHz phased array probe. Patients will be scanned in supine position by a recording 5 seconds videos. LUS will be assessed for the presence of B lines.
The sum of lung comets produces a score reflecting the extent of lung water accumulation. LUS will be obtained by scanning 12-rib interspaces. The sum of B-lines on each scanning site yields a score from 0 to 36
Interventions
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volume controlled ventilation
Lung ultrasound (LUS) will be performed with a 2-4 MHz phased array probe. Patients will be scanned in supine position by a recording 5 seconds videos. LUS will be assessed for the presence of B lines.
The sum of lung comets produces a score reflecting the extent of lung water accumulation. LUS will be obtained by scanning 12-rib interspaces. The sum of B-lines on each scanning site yields a score from 0 to 36
pressure controlled ventilation
Lung ultrasound (LUS) will be performed with a 2-4 MHz phased array probe. Patients will be scanned in supine position by a recording 5 seconds videos. LUS will be assessed for the presence of B lines.
The sum of lung comets produces a score reflecting the extent of lung water accumulation. LUS will be obtained by scanning 12-rib interspaces. The sum of B-lines on each scanning site yields a score from 0 to 36
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Left Ventricular ejection fraction less than 40%.
* Any patient known to have pulmonary hypertension
* Patients with preoperative congestive heart failure, cardiogenic shock, preoperative pulmonary edema
* Hepatic patients (liver functions double the upper reference range)
* Morbid obesity (BMI \> 40).
* Renally impaired patients with creatinine more than 2 mg/dl.
* Any patient with respiratory dysfunction (FEV1\<60% of the expected).
* Any patient with previous thoracic surgery.
* One lung ventilation more than 2 hours
18 Years
60 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Hisham Hosny
Associate professor
Principal Investigators
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Hisham Hosny, MD
Role: PRINCIPAL_INVESTIGATOR
Kasr Al-Ainy Faculty of Medicine
Locations
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Kasr Al-Ainy faculty of medicine. Cairo University
Cairo, , Egypt
Countries
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Other Identifiers
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AnesthN-8-2018
Identifier Type: -
Identifier Source: org_study_id
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