The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

72 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-01

Study Completion Date

2023-04-30

Brief Summary

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In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery in the prone position.

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Detailed Description

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The VCV (volume controlled ventilation) mode is the mode commonly used in general anesthesia practice. In VCV mode, the parameters under control are tidal volume and respiratory rate. In VCV mode, airway pressure changes depending on resistance and compliance. There is a risk of increased airway pressures in this mode.

In PCV-VG (pressure controlled volume guaranteed ventilation) mode, the parameters under control are the peak airway inspiratory pressure and the I/E ratio. It has been shown that peak airway pressures decrease and partial oxygen pressure increase due to decreased inspiratory flow in this ventilation mode.

Both ventilation modes are frequently used in patients undergoing general anesthesia.

In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics (pulmonary peak-plateau pressure, compliance, driving pressure, SpO2 and end-tidal carbon dioxide) and hemodynamics (mean arterial pressure and heart rate) in patients undergoing vertebral surgery in the prone position.

In the study, patients will be randomized and divided into 2 groups after obtaining informed consent forms. If a mode change is required during the surgery, that patient will be excluded from the study.

Conditions

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Mechanical Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group PCV-VG

In this group, pressure-controlled volume guaranteed ventilation (PCV- VG) was applied in patients undergoing vertebral surgery in the prone position.

The mechanical ventilation mode

Intervention Type DEVICE

Changing the mechanical ventilation mode

Group VCV

In this group, volume-controlled ventilation (VCV) was applied in patients undergoing vertebral surgery in the prone position.

The mechanical ventilation mode

Intervention Type DEVICE

Changing the mechanical ventilation mode

Interventions

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The mechanical ventilation mode

Changing the mechanical ventilation mode

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients who will undergo thoracolumbar vertebral surgery in the prone position
* Patients older than 18 years
* Patients younger than 70 years of age
* ASA 1-2 patients

Exclusion Criteria

* Patients with a BMI \>30 kg/m2
* Patients with a history of chronic pulmonary disease
* Patients with a history of previous thoracic surgery
* Patients with ASA \>3
* Patients who will undergo emergency surgery
* Pregnant patients

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes