Pressure Controlled Ventilation Versus Volume Controlled Ventilation in Upper Abdominal Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-05

Study Completion Date

2022-12-05

Brief Summary

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Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation

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Detailed Description

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The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)

Conditions

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Ventilator Lung

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Group 1

group 1 starts with volume controlled ventilation

Group Type OTHER

Starting with volume controlled ventilation and changing the ventilation mode every 20 minutes

Intervention Type OTHER

group 1 starts with volume controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to pressure controlled ventilation after letting washout we take three consecutive measurements at pressure controlled ventilation and we will repeat this protocol during surgery

Group 2

group 2 starts with pressure controlled ventilation

Group Type OTHER

Starting with pressure controlled ventilation and changing the ventilation mode every 20 minutes

Intervention Type OTHER

group 2 starts with pressure controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to volume controlled ventilation after letting washout we take three consecutive measurements at volume controlled ventilation and we will repeat this protocol during surgery

Interventions

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Starting with volume controlled ventilation and changing the ventilation mode every 20 minutes

group 1 starts with volume controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to pressure controlled ventilation after letting washout we take three consecutive measurements at pressure controlled ventilation and we will repeat this protocol during surgery

Intervention Type OTHER

Starting with pressure controlled ventilation and changing the ventilation mode every 20 minutes

group 2 starts with pressure controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to volume controlled ventilation after letting washout we take three consecutive measurements at volume controlled ventilation and we will repeat this protocol during surgery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ASA1-2 , \>18 years old patients having upper abdominal surgery

Exclusion Criteria

* chronic obstructive lung disease, interstitial lung disease
* chronic renal failure
* Child-Pugh \> 6 liver disease
* Patients who don't give consent
* NYHA \> 2 heart failure

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes