Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery.
NCT ID: NCT04815733
Last Updated: 2023-04-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
106 participants
INTERVENTIONAL
2017-06-01
2023-03-31
Brief Summary
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Detailed Description
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Intervention: We plan to include 100 patients who will undergo elective long (more 2 hours) laparoscopic or abdominal robotic surgery. All patients will be randomly assigned in two groups in ratio 1:1. 1 group- deep neuromuscular block and mandatory ventilation; 2 group- partial neuromuscular block and pressure support ventilation.
Expected Results. PSV may reduce the systemic inflammatory response compared to the mandatory ventilation during laparoscopic and abdominal robotic surgery.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
Randomization of patients into two 1:1 groups will be performed by random number generation.
PREVENTION
DOUBLE
Study Groups
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Mandatory ventilation
deep neuromuscular block and mandatory ventilation (PCV-VG);
Mandatory ventilation
Use PCV-VG
Pressure support ventilation
partial neuromuscular block and pressure support ventilation (PSVpro).
pressure support ventilation
Use PSVpro
Interventions
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Mandatory ventilation
Use PCV-VG
pressure support ventilation
Use PSVpro
Eligibility Criteria
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Inclusion Criteria
* Men and women aged 18 years or more.
* The physical status from ASA classification I, II or III.
* BMI \<= 34.9 kg / m2.
* Low risk of respiratory complications.
* Laparoscopic surgery in the pelvis.
Exclusion Criteria
* BMI\> = 35 kg / m2.
* Neuromuscular disease.
* Allergy to Anesthetic Agents.
* Operations on two cavities.
* Operations on the chest cavity.
18 Years
ALL
Yes
Sponsors
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Moscow Clinical Scientific Center
OTHER
Responsible Party
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Valerii Subbotin
PhD
Locations
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Moscow Clinical Scientific Center
Moscow, , Russia
Countries
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Other Identifiers
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MoscowCSC
Identifier Type: -
Identifier Source: org_study_id
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