Controlling Post-extraction Complications of Impacted Mandibular Third Molar

NCT ID: NCT04816253

Last Updated: 2021-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-10

Study Completion Date

2021-06-20

Brief Summary

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Impacted mandibular 3rd molar will be extracted in all patients, then patients will be divided, according to material placed in extraction socket into 3 groups: control, hyaluronic acid and honey. Then post extraction complications will be evaluated

Detailed Description

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Impacted Mandibular third molar will be extracted under local anesthesia Through standard surgical flap elevation, after extraction and wound irrigation a material facilitate healing will be placed. According to material will be placed patients will be divide into 3 group: control ( no material, second group hyaluronic acid, third group ( honey).. then wound will be closed. Postoperative pain ( through visual analog scale) , edema, total dose of analgesic, mandibular movement (interincisal distance in mm) will be evaluated preoperative, 1,2,3,7, and 10 day after extraction

Conditions

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Preventing Postextraction Complication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Normal saline

Normal saline irrigation after extraction and No drug placed in tooth socket

Group Type PLACEBO_COMPARATOR

Normal saline

Intervention Type DRUG

Normal saline irrigation and No other drug placed after extraction

Gengigel

Gengigel (Hyaluronic acid) placed after extraction

Group Type ACTIVE_COMPARATOR

Hyaluronic acid

Intervention Type DRUG

Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket

Methylprednisolone

Methylprednisolone will be given intravenous to a patient half an hour before the surgery

Group Type ACTIVE_COMPARATOR

Methylprednisolone

Intervention Type DRUG

Methylprednsolone will be injected half an hour preoperatively

Methylprednisolone and Gengigel

Methylprednisolone will be given intravenous to a patient half an hour before the surgery and Gengigel (Hyaluronic acid) placed after extraction

Group Type ACTIVE_COMPARATOR

Methylprednisolone and Hyaluronic acid

Intervention Type DRUG

Methylprednisolone will be injected half an hour preoperatively and Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket

Interventions

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Normal saline

Normal saline irrigation and No other drug placed after extraction

Intervention Type DRUG

Hyaluronic acid

Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket

Intervention Type DRUG

Methylprednisolone

Methylprednsolone will be injected half an hour preoperatively

Intervention Type DRUG

Methylprednisolone and Hyaluronic acid

Methylprednisolone will be injected half an hour preoperatively and Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket

Intervention Type DRUG

Other Intervention Names

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Gengigel

Eligibility Criteria

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Inclusion Criteria

* healthy patients
* patient has impacted 3rd molar

Exclusion Criteria

* medically compromised patients Heavy smoking patients
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Alaa Altaweel

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Vision college

Jeddah, , Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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Extraction healing

Identifier Type: -

Identifier Source: org_study_id

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