Distolingual Infiltration Verses Conventional Nerve Block in Mandibular Third Molar Extraction

NCT ID: NCT07296926

Last Updated: 2026-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-15

Study Completion Date

2026-04-15

Brief Summary

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This randomized controlled trial will compare the effectiveness of adding distolingual infiltration to conventional inferior alveolar and buccal nerve blocks for mandibular third molar extraction. A total of 120 patients will be allocated into two groups. Pain during flap elevation and bone guttering will be assessed using the Visual Analogue Scale.

Detailed Description

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Mandibular third molar extraction is a common oral and maxillofacial surgery procedure that requires profound local anesthesia. Despite conventional inferior alveolar, lingual and buccal nerve blocks, the distolingual gingiva may remain non-anesthetized due to accessory innervation via the mylohyoid and other nerves. Distolingual infiltration may improve anesthesia in this area.

This randomized controlled trial will enroll 120 patients requiring mandibular third molar extraction. Participants will be randomized into two groups: conventional inferior alveolar and buccal nerve block (Group A) and the same technique with additional distolingual infiltration (Group B). Pain during mucoperiosteal flap elevation and bone guttering will be recorded on a 0-10 Visual Analogue Scale. The primary objective is to determine whether distolingual infiltration improves pain control compared to the conventional technique.

Conditions

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Pain (Visceral, Somatic, or Neuropathic)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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conventional nerve block injection

Inferior alveolar and buccal nerve block using 2% lignocaine with adrenaline (1:80,000) without distolingual infiltration.

Group Type ACTIVE_COMPARATOR

Conventional Inferior Alveolar and Buccal Nerve Block

Intervention Type PROCEDURE

Standard inferior alveolar and long buccal nerve block for mandibular third molar extraction.

conventional inferior alveolar with distolingual infilterate injection

Inferior alveolar supplemented with distolingual infiltration using 2% lignocaine with adrenaline (1:80,000).

Group Type EXPERIMENTAL

Distolingual Infiltration plus Conventional Nerve Block

Intervention Type PROCEDURE

Distolingual infiltration (0.2 ml) administered in addition to conventional inferior alveolar during mandibular third molar extraction.

Interventions

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Conventional Inferior Alveolar and Buccal Nerve Block

Standard inferior alveolar and long buccal nerve block for mandibular third molar extraction.

Intervention Type PROCEDURE

Distolingual Infiltration plus Conventional Nerve Block

Distolingual infiltration (0.2 ml) administered in addition to conventional inferior alveolar during mandibular third molar extraction.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Healthy individuals

* Male and female
* Age 18-45 years
* Mandibular third molar impaction - all positions
* Mandibular third molar impaction - all classes

Exclusion Criteria

* ASA status III and above

* Patients requiring multiple extractions in the same appointment
* Allergy to lignocaine
* Patients in whom adrenaline is contraindicated
* Medically compromised individuals e.g. poorly controlled diabetes, hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Watim Medical & Dental College

OTHER

Sponsor Role lead

Responsible Party

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aimen zafar

prinicpal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Dr Aimen Zafar

Islamabad, , Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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dr aimen zafar Aimen zafar, bds

Role: CONTACT

+923361056720

Facility Contacts

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aimen zafar zafar masood, bds

Role: primary

00923361056720

Other Identifiers

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DSG-2023-335-4631-A

Identifier Type: -

Identifier Source: org_study_id

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