Effect of Honey and Dexamethason on Extraction Healing

NCT ID: NCT04848259

Last Updated: 2021-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-05

Study Completion Date

2021-06-27

Brief Summary

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Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated

Detailed Description

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Patient with impacted lower third molar will be selected to this study agording to agent applied preoperative. Group 1 will receive topical honey and Group 2 will receive IV dexamethason. After surgical removal of impacted tooth under local anesthesia postoperative pain mouth opening, and swelling will be evaluated

Conditions

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Impacted Third Molar Tooth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Control

No drug given before surgery

Group Type PLACEBO_COMPARATOR

Normal saline

Intervention Type DRUG

Saline will be applied after surgery

Dexamethason

Dexamethason will be given IV before surgery

Group Type ACTIVE_COMPARATOR

Dexamethasone

Intervention Type DRUG

Dexamethason will be given IV before surgery

Natural honey

Honey will be placed locally after impaction removal

Group Type ACTIVE_COMPARATOR

Honey

Intervention Type DRUG

Honey will be applied locally after surgery

Dexamethason and natural honey

Dexamethason will be given IV before surgery and Honey will be placed locally after impaction removal

Group Type ACTIVE_COMPARATOR

Dexamethasone and honey

Intervention Type DRUG

Dexamethason will be given IV before surgery and then Honey will be applied locally after surgery

Interventions

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Normal saline

Saline will be applied after surgery

Intervention Type DRUG

Dexamethasone

Dexamethason will be given IV before surgery

Intervention Type DRUG

Honey

Honey will be applied locally after surgery

Intervention Type DRUG

Dexamethasone and honey

Dexamethason will be given IV before surgery and then Honey will be applied locally after surgery

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* impacted 3rd molar
* healthy patient No smoking

Exclusion Criteria

* history of smoking Medical disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Alaa Altaweel

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Vision colleges

Jeddah, , Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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Impaction

Identifier Type: -

Identifier Source: org_study_id

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