The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar

NCT ID: NCT06809855

Last Updated: 2025-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-20

Study Completion Date

2024-10-16

Brief Summary

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Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.

Methods: A split mouth technique on 16 patients with bilateral similar impacted mandibular third molar were extracted; one side was given 8mg intramuscular injection of dexamethasone (study group) and the other side wasn't given injection (control group) and compare of the two sides were done in the following seven days.

Detailed Description

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Conditions

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Dexamethasone Administration Post Extraction Complication

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Each patient resembles the study group in which the patient is injected intramuscularly by a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar on one side and control group on which the impacted mandibular third molar on the other side is removed without usage of 8mg dexamethasone.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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dexamethasone immediate injection postoperatively

intramuscular injection of a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar

Group Type ACTIVE_COMPARATOR

Dexamethasone

Intervention Type DRUG

single 8mg post-operative intramuscular injection

no intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Dexamethasone

single 8mg post-operative intramuscular injection

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* bilateral similar impacted lower third molar
* willing to do surgical extraction

* allergic to dexamethasone
* who has medical diseases
* taking any medications
* pregnant or lactating women
Minimum Eligible Age

15 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yassir R. Al-khannaq

OTHER

Sponsor Role lead

Responsible Party

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Yassir R. Al-khannaq

lecturer Dr.

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad

Baghdad, , Iraq

Site Status

Countries

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Iraq

Other Identifiers

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997124

Identifier Type: -

Identifier Source: org_study_id

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