Effect of Physical Therapy Exercises on Cardiorespiratory Fitness Level in COVID19 Patients After Recovery.

NCT ID: NCT04445376

Last Updated: 2020-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-03

Study Completion Date

2020-10-03

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In some patients, lung function declined by about 20 to 30% after recovery. Computer tomography of COVID-19 patients revealed a ground glass opacity in both lungs. We will measure the Cardiorespiratory fitness according to American College of Sports medicine guidline and provide physiotherapy exercise to the patients to measure the improvement.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

In December 2019, the first reports emerged of a novel severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) in Wuhan, China. The virus, which causes atypical pneumonia progressing to acute lung injury and acute respiratory distress syndrome (ARDS) in some individuals, was named COVID-19. The burden of fibrotic lung disease following SARS-CoV-2 infection is likely to be high; therefore, given the scale of the pandemic, the global burden of fibrotic lung disease will probably increase considerably. The aim of this study is to check the cardiorespiratory fitness level and the effect of Physical therapy intervention to improve the Cardiorespiratory fitness level in patients recovered from COVID-19. Quality of life has also been affected due to COVID19 due to decreased Cardiorespiratory fitness level, and this study also aims to improve the quality of life of people recovered from COVID19.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Covid19

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Intervention Group (Ventilatory)

Breathing Exercise and Aerobic Training will be provided to all the patients.The training session will be given 3 days a week.

Group Type EXPERIMENTAL

Physical Exercises

Intervention Type OTHER

Aerobic Training and Breathing Exercises.

Intervention (Non ventilatory)

Breathing Exercise and Aerobic Training will be provided to all the patients.The training session will be given 3 days a week.

Group Type EXPERIMENTAL

Physical Exercises

Intervention Type OTHER

Aerobic Training and Breathing Exercises.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Physical Exercises

Aerobic Training and Breathing Exercises.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Recovered from COVID 19 disease (PCR report).
* Sub-normal performance as compared to normative data.
* Do not have any Respiratory Problem.
* Consent to participate in the study.
* Able to understand and perform the exercise.
* Age from 18 to 75.
* Dyspnea due to COVID19.
* Modified Borg Dyspnea Scale score at least 2 but less than 7.

Exclusion Criteria

* Not suffered from COVID 19.
* Respiratory Problem.
* Resting Blood Pressure greater than 160/100 instead of taking medicine
* Greater than 1-month post COVID19 Recovery.
* Cardiorespiratory comorbidities which limit participation in exercise.
* Any Musculoskeletal problem which limit participation in Training.
* Other cardiovascular morbidity which would limit exercise tolerance (heart failure, abnormal blood pressure responses or ST-segment depression \> 2mm, symptomatic aortic stenosis, complex arrhythmias).
* Unstable angina
* Orthostatic blood pressure decrease of \>20 mmHg with symptoms
* Hypertropic cardiomyopathy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Government College University Faisalabad

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Ishtiaq Ahmed

Physiotherapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ishtiaq Ahmed, DPT

Role: PRINCIPAL_INVESTIGATOR

Government College University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Bin Inam Rehabilitation Center.

Faisalābad, Punjab Province, Pakistan

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Pakistan

References

Explore related publications, articles, or registry entries linked to this study.

George PM, Wells AU, Jenkins RG. Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy. Lancet Respir Med. 2020 Aug;8(8):807-815. doi: 10.1016/S2213-2600(20)30225-3. Epub 2020 May 15.

Reference Type BACKGROUND
PMID: 32422178 (View on PubMed)

Belli S, Balbi B, Prince I, Cattaneo D, Masocco F, Zaccaria S, Bertalli L, Cattini F, Lomazzo A, Dal Negro F, Giardini M, Franssen FME, Janssen DJA, Spruit MA. Low physical functioning and impaired performance of activities of daily life in COVID-19 patients who survived hospitalisation. Eur Respir J. 2020 Oct 15;56(4):2002096. doi: 10.1183/13993003.02096-2020. Print 2020 Oct.

Reference Type BACKGROUND
PMID: 32764112 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

313

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.