Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2019-09-30
2020-02-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
QUADRUPLE
Study Groups
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stage 3 periodontitis
GCF and serum samples were collected before and after treatment from periodontitis patients.
Non-surgical periodontal treatment
Scaling and root planing (SRP), in four clinical visits
Oral hygiene instructions
Oral hygiene instructions includes brushing with the modified Bass technique, interdental cleaning with dental floss and interdental brushes.
Periodontally healthy controls
GCF and serum samples were collected from periodontally healthy controls at baseline for once.
Oral hygiene instructions
Oral hygiene instructions includes brushing with the modified Bass technique, interdental cleaning with dental floss and interdental brushes.
Interventions
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Non-surgical periodontal treatment
Scaling and root planing (SRP), in four clinical visits
Oral hygiene instructions
Oral hygiene instructions includes brushing with the modified Bass technique, interdental cleaning with dental floss and interdental brushes.
Eligibility Criteria
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Inclusion Criteria
2. having at least 20 natural teeth, excluding third molars
3. having no systemic disease
4. non-smokers
5. criteria for healthy control group: BOP \< 10% and PD ≤ 3 mm without clinical attachment loss or radiographic sign of alveolar bone destruction
6. criteria for stage 3 periodontitis group: interdental CAL ≥ 5 mm at least 2 non-adjacent teeth, PD ≥ 6 mm and radiographic bone loss extending to the mid-third of the root or beyond.
Exclusion Criteria
2. smoking
3. current pregnancy or lactation
4. a history of periodontal treatment in the past 6 months
5. using antibiotic, anti-inflammatory drugs or any other drugs within the past 6 months.
26 Years
49 Years
ALL
Yes
Sponsors
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Giresun University
OTHER
Bulent Ecevit University
OTHER
Aydin Adnan Menderes University
OTHER
Responsible Party
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Zeynep Pinar KELES YUCEL
Assistant Prof.
Locations
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Giresun University
Giresun, , Turkey (Türkiye)
Countries
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Other Identifiers
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KAEK-92
Identifier Type: -
Identifier Source: org_study_id
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