Analysis of the Impact of Contemporary Subgingival Debridement Techniques on Immunological Biomarkers in Gingival Crevicular Fluid
NCT ID: NCT07243145
Last Updated: 2025-11-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
80 participants
OBSERVATIONAL
2024-10-15
2025-05-15
Brief Summary
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METHOD: The study comprised 80 nonsmoking, systemically healthy volunteers. Patients were divided into two groups at random: the Guided Biofilm Therapy (GBT) group and the convetional therapy group, which included Gracey curette and an ultrasonic device. All patients were assessed before and one and three months after therapy for clinical characteristics like pocket depth, Gingival Index (GI), Plaque Index (PI), Bleeding on Probing Index (BOP), and the levels of IL-1β, IL-10, TNF-α, and MMP-8 in gingival crevicular fluid (GCF).
RESULTS: ... CONCLUSION:...
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Detailed Description
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METHOD: The study comprised 80 nonsmoking, systemically healthy volunteers. Patients were divided into two groups at random: the Guided Biofilm Therapy (GBT) group and the convetional therapy group, which included Gracey curette and an ultrasonic device. All patients were assessed before and one and three months after therapy for clinical characteristics like pocket depth, Gingival Index (GI), Plaque Index (PI), Bleeding on Probing Index (BOP), and the levels of IL-1β, IL-10, TNF-α, and MMP-8 in gingival crevicular fluid (GCF).
RESULTS: ... CONCLUSION:...
Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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1.Group: The Conventional Treatment
Cavitron and Gracey curette (the standard technique) was utilized for subgingival debridement
No interventions assigned to this group
2. group: Guided biofilm therapy
Subgingival debridement was carried out using the GBT approach, which involved following the protocol's directions properly.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Completed periodontal diagnostic data (Gingival Index, Plaque Index, Periodontal pocket depths, Attachment loss, Radiological data, and Bone loss data)
* Did not take anti-inflammatory drugs in the previous month
* Volunteered to participate with Stage 1-2 periodontitis.
Exclusion Criteria
* Pregnant or lactating patients
* Smokers
* Patients who did not wish to participate in the study were excluded
18 Years
40 Years
ALL
Yes
Sponsors
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Nigde Omer Halisdemir University
OTHER
Niğde Ömer Halisdemir University
UNKNOWN
Selcen Ozcan Bulut
OTHER
Responsible Party
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Selcen Ozcan Bulut
Nigde Omer Halisdemir University
Locations
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Nigde Omer Halisdemir University
Niğde, , Turkey (Türkiye)
Countries
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Other Identifiers
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2023/87
Identifier Type: -
Identifier Source: org_study_id
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