Evaluation of Biomarker Levels in Blood, Saliva and Gingival Fluid in Periodontitis
NCT ID: NCT04647123
Last Updated: 2020-11-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
40 participants
OBSERVATIONAL
2020-01-01
2021-03-01
Brief Summary
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Detailed Description
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The aim of this study is to compare Ischemia-modified albumin (IMA), malondialdehyde (MDA), Catalase (CAT), Glutathione (GSH) and Adenosine deaminase (ADA) levels in gingival crevicular fluid, serum and saliva of periodontally hopeless, periodontitis and gingivitis teeth with healthy control groups.
In this study, 25 periodontally healthy individuals (control group) and 25 individuals with various levels of periodontal disease in different teeth will be included.
Gingival crevicular fluid, saliva and blood samples will be taken from patients with periodontally healthy teeth without any treatment.
In patients diagnosed with periodontal disease, teeth will be divided into 3 subgroups as hopeless, periodontitis and gingivitis. In patients with a diagnosis of periodontal disease, saliva and blood samples will be taken twice, before and after the training of scaling and root planing, desperate tooth extraction, oral hygiene motivation.
Conditions
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Keywords
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Hopeless teeth
The teeth that can not be treated periodontally and who are desperate for extraction will be included in this group.
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
Periodontitis
Teeth diagnosed with periodontitis will be included in this group.
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
Gingivitis
Teeth diagnosed with gingivitis will be included in this group.
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
Healthy
Teeth diagnosed with helthy will be included in this group.
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
Interventions
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No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
65 Years
ALL
No
Sponsors
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Yuzuncu Yıl University
OTHER
Responsible Party
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Hacer Sahin Aydinyurt
Assoc. Prof.
Principal Investigators
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hacer sahin aydınyurtt, assoc. prof
Role: PRINCIPAL_INVESTIGATOR
Yuzuncu Yıl University
Locations
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Van yuzuncu yil university
Van, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Hacer Sahin aydınyurt, Assoc. Prof.
Role: primary
Other Identifiers
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: 06.06.2018/09
Identifier Type: -
Identifier Source: org_study_id