Bactericidal Permeability Protein Inhibitor and Interleukin-1beta Levels After Non-surgical Periodontal Treatment
NCT ID: NCT06354504
Last Updated: 2024-04-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
30 participants
INTERVENTIONAL
2019-11-19
2020-09-20
Brief Summary
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Detailed Description
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Objective: It is the evaluation of periodontal disease effect of BPI and interleukin-1 beta (IL-1 β) levels in gingival fluid before and after non-surgical periodontal treatment (NSPT)in patients with periodontal disease.
Method: Thirty systemically healthy and non-smoking individuals with periodontitis were included in the study. Before NSPT, the clinical parameters of plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAS), bleeding on probing (BOP) were measured. The gingival fluid samples were taken using the paper strip method. The same procedures were repeated at 6 weeks and 6 months after non-surgical periodontal treatment. ELISA method was used for the analysis of the samples
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Healty
Non-surgical periodontal treatment
Non-surgical periodontal treatment
Scaling and root planing in two sessions over the course of a 48-hour period comprised the standard treatment procedure
Interventions
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Non-surgical periodontal treatment
Scaling and root planing in two sessions over the course of a 48-hour period comprised the standard treatment procedure
Eligibility Criteria
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Inclusion Criteria
* Stage II or III, Grade A periodontitis
* Having at least 20 permanent teeth (excluding third molars and any tooth loss induced by -non-periodontal causes).
Exclusion Criteria
* use of alcohol; pregnancy or lactation; intake ofantibiotics, steroidal or non-steroidal anti-inflammatory drugs within the last 6 months
* having received periodontal treatment within the last 6 months
22 Years
64 Years
ALL
Yes
Sponsors
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Akdeniz University
OTHER
Responsible Party
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Nezahat Arzu Kayar
Clinical Professor
Locations
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Akdeniz Üniversity
Antalya, , Turkey (Türkiye)
Akdeniz Üniversitesi Diş Hekimliği Fakültesi
Antalya, , Turkey (Türkiye)
Countries
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Other Identifiers
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20.02.2019/177
Identifier Type: -
Identifier Source: org_study_id
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