Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
57 participants
OBSERVATIONAL
2012-03-31
2018-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Patients
Patients with propionic acidemia, isovaleric acidemia, methylmalonic acidemia
No intervention
No intervention, observational study with metabolic characterisation
Controls
Healthy humans
No intervention
No intervention, observational study with metabolic characterisation
Interventions
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No intervention
No intervention, observational study with metabolic characterisation
Eligibility Criteria
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Inclusion Criteria
* age\>5 years
Exclusion Criteria
* contraindications for an oral glucose tolerance test such as fasting blood glucose \>126 mg/dl, severe chronic gastrointestinal conditions, allergy against black currant
* contraindications for magnetic resonance tomography (MRT) such as claustrophobia, metallic implants which are not MRT compatible
5 Years
ALL
Yes
Sponsors
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University Children's Hospital, Düsseldorf
UNKNOWN
German Diabetes Center
OTHER
Responsible Party
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Principal Investigators
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Michael Roden, Professeor
Role: PRINCIPAL_INVESTIGATOR
German Diabetes Center
Regina Ensenauer, Professor
Role: PRINCIPAL_INVESTIGATOR
Children's Hospital Düsseldorf
Locations
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Department of General Pediatrics, Neonatology and Pediatric Cardiology of the University Children's Hospital Düsseldorf
Düsseldorf, North Rhine-Westphalia, Germany
Institute for Clinical Diabetology, German Diabetes Center
Düsseldorf, North Rhine-Westphalia, Germany
Countries
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Other Identifiers
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MITO-MRS
Identifier Type: -
Identifier Source: org_study_id
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