Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2020-09-11
2021-05-21
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
NONE
Study Groups
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Short overnight fast
Overnight fasting duration intervention: Participants will receive their last evening meal at 11 pm and stay overnight fasted afterwards for (9.5h).
Overnight fasting duration
Subjects will adhere to overnight fasting protocol for 1 day
Long overnight fast
Overnight fasting duration intervention: Participants will receive their last evening meal at 4.30 pm and stay overnight fasted afterwards for (16h).
Overnight fasting duration
Subjects will adhere to overnight fasting protocol for 1 day
Interventions
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Overnight fasting duration
Subjects will adhere to overnight fasting protocol for 1 day
Eligibility Criteria
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Inclusion Criteria
* Caucasian (people will be excluded when having a ≥50% racial African/Asian background)
* Participants should have suitable veins for cannulation or repeated venipuncture
* Women are post-menopausal (defined as at least 1 year post cessation of menses)
* Men and women aged ≥ 45 and ≤ 75 years at the start of the study
* Body mass index (BMI) 18.5 - 25 kg/m2
* Stable dietary habits (no weight loss or gain \>3kg in the past 3 months)
* Sedentary lifestyle (not more than 3 hours of vigorous sports per week)
Exclusion Criteria
* Active diseases (cardiovascular, diabetes, liver, kidney, cancer or other)
* Any contraindication for MRI scanning
* Alcohol consumption of \>2 servings per day
* Regular smoking
* No use of medication interfering with investigated study parameters (as determined by responsible physician)
* Participants who do not want to be informed about unexpected medical findings, or do not wish that their physician
45 Years
75 Years
ALL
Yes
Sponsors
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Maastricht University
OTHER
Responsible Party
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Charlotte Andriessen
Principal Investigator
Principal Investigators
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Vera Schrauwen-Hinderling, Dr
Role: PRINCIPAL_INVESTIGATOR
Principal Investigator
Locations
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Maastricht University
Maastricht, Limburg, Netherlands
Countries
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Other Identifiers
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NL72118.068.20
Identifier Type: -
Identifier Source: org_study_id
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