Effects of Fasting and Exercise on Insulin and GH Signaltransduction in Muscle and Fat
NCT ID: NCT00817440
Last Updated: 2011-01-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
8 participants
INTERVENTIONAL
2008-12-31
Brief Summary
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Primarily we will investigate markers for GH and insulin signaltransduction in muscle- and fat-biopsies after fasting for 72 hours and after 1 hour of ergometer-cycling at 65% Vo2max.
In addition to this we will investigate the effect of fasting and exercise on the velocity of carbamide synthesis, aminoacid rate of turnover and glucose rate of turnover.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
NONE
Study Groups
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Control
control: muscle and fat biopsies and basal aminoacid and glucose turnover
No interventions assigned to this group
Exercise
1 hour ergometer cycling on 65% of Vo2max, and then the same as arm 1.
Exercise
1 hour ergometer cycling on 65% of Vo2max, and then the same as arm 1.
Fasting
3 days of fasting and then the same as arm 1
Fasting
3 days of fasting and then the same as arm 1
Interventions
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Exercise
1 hour ergometer cycling on 65% of Vo2max, and then the same as arm 1.
Fasting
3 days of fasting and then the same as arm 1
Eligibility Criteria
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Inclusion Criteria
* Body mass index (BMI) 20-26
* age 18-45 years
Exclusion Criteria
* any use of medicine
18 Years
45 Years
MALE
Yes
Sponsors
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University of Aarhus
OTHER
Responsible Party
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endokrinologiskforskningslaboratorium M, Aarhus sygehus
Locations
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Aarhus sygehus
Aarhus, Jylland, Denmark
Countries
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Other Identifiers
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16.12.2008
Identifier Type: -
Identifier Source: org_study_id
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