Investigating Transcranial Direct Current Stimulation (tDCS) in Accelerating Learning in a Healthy Older Population

NCT ID: NCT03467698

Last Updated: 2024-01-09

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-21

Study Completion Date

2022-10-21

Brief Summary

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The overall objective of this study is to explore whether transcranial Direct Current Stimulation (tDCS) can accelerate associative learning and boost associative memory in healthy subjects.

Detailed Description

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The overall objective of this study is to explore whether transcranial Direct Current Stimulation (tDCS) can accelerate associative learning and boost associative memory in healthy subjects.

The aim of this study is to investigate the effects of transcranial Direct Current Stimulation (tDCS) stimulation during a verbal paired-associate learning task to determine if tDCS may be used as a way to enhance brain plasticity during an associative memory task, and to accelerate learning and to optimize associative memory performance. We hypothesize that participants who receive tDCS stimulation will improve their associative memory performance.

Conditions

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Associative Memory in Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants will be randomly assigned to one of two groups: (1) active tDCS (2) Sham tDCS.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Active tDCS

active HD-tDCS will be administered

Group Type EXPERIMENTAL

Active tDCS

Intervention Type DEVICE

Real stimulation

Sham tDCS

sham HD-tDCS will be administered

Group Type SHAM_COMPARATOR

Sham tDCS

Intervention Type DEVICE

Sham stimulation

Interventions

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Active tDCS

Real stimulation

Intervention Type DEVICE

Sham tDCS

Sham stimulation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Age between 55 and 75
2. Currently not using any medication contradicting with tDCS
3. Native English speaker
4. Capable of understanding and signing an informed consent

Exclusion Criteria

1. Acquainted with the Swahili language or culture
2. Severe disease
3. Mental illness
4. Cardiac history
5. History of severe head injuries
6. History of epileptic insults
7. Any implanted devices such as pace maker, neurostimulator
8. Pregnancy
Minimum Eligible Age

55 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The University of Texas at Dallas

OTHER

Sponsor Role lead

Responsible Party

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Sven Vanneste

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sven Vanneste, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas at Dallas

Locations

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University of Texas at Dallas

Richardson, Texas, United States

Site Status

Countries

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United States

References

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Luckey AM, McLeod SL, Robertson IH, To WT, Vanneste S. Greater Occipital Nerve Stimulation Boosts Associative Memory in Older Individuals: A Randomized Trial. Neurorehabil Neural Repair. 2020 Nov;34(11):1020-1029. doi: 10.1177/1545968320943573. Epub 2020 Sep 23.

Reference Type DERIVED
PMID: 32964776 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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18-40

Identifier Type: -

Identifier Source: org_study_id

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