Investigating Memory Retrieval Improvement in Healthy Subjects

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-27

Study Completion Date

2024-09-05

Brief Summary

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The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

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Detailed Description

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Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.

Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether learning can be accelerated and associative memory improved by using tDCS, this study will compare the performance in a Face Name Associate memory task from 3 groups. The first group will get active aodal tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task and the third group will get active cathodal tDCS.

Conditions

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Healthy Adults

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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active anodal tDCS

active anodal tDCS with Face Name associate Memory task

Group Type EXPERIMENTAL

active anodal tDCS

Intervention Type DEVICE

active anodal tDCS with memory task

Sham tDCS

sham tDCS with Face Name associate Memory task

Group Type SHAM_COMPARATOR

sham tDCS

Intervention Type DEVICE

sham tDCS with memory task

active cathodal tDCS

active cathodal tDCS with Face Name associate Memory task

Group Type EXPERIMENTAL

active cathodal tDCS

Intervention Type DEVICE

active cathodal tDCS with memory task

Interventions

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active anodal tDCS

active anodal tDCS with memory task

Intervention Type DEVICE

sham tDCS

sham tDCS with memory task

Intervention Type DEVICE

active cathodal tDCS

active cathodal tDCS with memory task

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age: 18-35 years Native English Speaker

Exclusion Criteria

* History of severe head injuries, epileptic insults, or heart disease. Severe psychiatric disorders and severe untreated medical problems. Contraindications for tDCS (pregnant women, implanted devices)

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes