SLeep and IMagery Correlates (SOMMEIL-IMAGERIE)

NCT ID: NCT03130322

Last Updated: 2025-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-09

Study Completion Date

2018-07-04

Brief Summary

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This study is designed to determine the neural networks underlying the sleep-related motor consolidation process following motor imagery practice. While beneficial effects of sleep are expected for sequential movement but not for adaptation motor tasks, the corresponding neuroanatomical correlates have not yet been investigated when participants acquired the motor tasks through mental practice. Data should substantially promote how designing motor imagery interventions targeting (re)learning and/or motor recovery in patients suffering from motor disorders.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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NightPP

Participants of the NightPP will be subjected to one MRI session and two MEG recording sessions: the first one before a physical practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Group Type EXPERIMENTAL

Imagery and Sleep questionnaires

Intervention Type OTHER

Participants complete a motor imagery questionnaire to assess their ability to form vivid mental images, as well as sleep questionnaires to control the quality of their sleep

MEG recordings (pre-test)

Intervention Type OTHER

Participants of the Day group perform two motor tasks (a finger sequential motor task and an adaptation motor task using a trackball) in the MEG, during a pre-test (Day 1 - 9h).

Task 1: Participants perform an 8-digit motor sequential task where each finger (except the thumb) is used twice. Performance is assessed by using a 4-keys keyboard. Participants are required to keep their fingers on the keys to minimize amplitude are instructed to tap the sequence as few errors as possible Task 2: Participants perform a motor adaptation task requiring scrolling a trackball to superimpose a geometric shape on another one, strictly similar but presented from another angle, as fast as possible.

Practice session

Intervention Type OTHER

Participants of the Day group perform a block of motor imagery practice of the two motor tasks.

MEG recordings (Post-test)

Intervention Type OTHER

Participants perform the two motor tasks in the MEG (post-test, strictly similar to the pre-test)

MRI

Intervention Type OTHER

The registration of the brain anatomy of each participant will be done by MRI 3D / T the week before the first experimental session.

NightMI

Participants of the NightMI will be subjected to one MRI session and two MEG recording sessions: the first one before a motor imagery practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Group Type EXPERIMENTAL

Imagery and Sleep questionnaires

Intervention Type OTHER

Participants complete a motor imagery questionnaire to assess their ability to form vivid mental images, as well as sleep questionnaires to control the quality of their sleep

MEG recordings (pre-test)

Intervention Type OTHER

Participants of the Day group perform two motor tasks (a finger sequential motor task and an adaptation motor task using a trackball) in the MEG, during a pre-test (Day 1 - 9h).

Task 1: Participants perform an 8-digit motor sequential task where each finger (except the thumb) is used twice. Performance is assessed by using a 4-keys keyboard. Participants are required to keep their fingers on the keys to minimize amplitude are instructed to tap the sequence as few errors as possible Task 2: Participants perform a motor adaptation task requiring scrolling a trackball to superimpose a geometric shape on another one, strictly similar but presented from another angle, as fast as possible.

Practice session

Intervention Type OTHER

Participants of the Day group perform a block of motor imagery practice of the two motor tasks.

MEG recordings (Post-test)

Intervention Type OTHER

Participants perform the two motor tasks in the MEG (post-test, strictly similar to the pre-test)

MRI

Intervention Type OTHER

The registration of the brain anatomy of each participant will be done by MRI 3D / T the week before the first experimental session.

NightCtrl

Participants of the NightCtrl will be subjected to one MRI session and two MEG recording sessions: the first one before a mental rotation practice session, a second MEG session right after practice,and second MEG session right after practice.

Group Type EXPERIMENTAL

Imagery and Sleep questionnaires

Intervention Type OTHER

Participants complete a motor imagery questionnaire to assess their ability to form vivid mental images, as well as sleep questionnaires to control the quality of their sleep

MEG recordings (pre-test)

Intervention Type OTHER

Participants of the Day group perform two motor tasks (a finger sequential motor task and an adaptation motor task using a trackball) in the MEG, during a pre-test (Day 1 - 9h).

Task 1: Participants perform an 8-digit motor sequential task where each finger (except the thumb) is used twice. Performance is assessed by using a 4-keys keyboard. Participants are required to keep their fingers on the keys to minimize amplitude are instructed to tap the sequence as few errors as possible Task 2: Participants perform a motor adaptation task requiring scrolling a trackball to superimpose a geometric shape on another one, strictly similar but presented from another angle, as fast as possible.

Practice session

Intervention Type OTHER

Participants of the Day group perform a block of motor imagery practice of the two motor tasks.

MEG recordings (Post-test)

Intervention Type OTHER

Participants perform the two motor tasks in the MEG (post-test, strictly similar to the pre-test)

MRI

Intervention Type OTHER

The registration of the brain anatomy of each participant will be done by MRI 3D / T the week before the first experimental session.

Day

Participants of the NightMI will be subjected to one MRI session and two MEG recording sessions: the first one before a motor imagery practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Group Type EXPERIMENTAL

Imagery and Sleep questionnaires

Intervention Type OTHER

Participants complete a motor imagery questionnaire to assess their ability to form vivid mental images, as well as sleep questionnaires to control the quality of their sleep

MEG recordings (pre-test)

Intervention Type OTHER

Participants of the Day group perform two motor tasks (a finger sequential motor task and an adaptation motor task using a trackball) in the MEG, during a pre-test (Day 1 - 9h).

Task 1: Participants perform an 8-digit motor sequential task where each finger (except the thumb) is used twice. Performance is assessed by using a 4-keys keyboard. Participants are required to keep their fingers on the keys to minimize amplitude are instructed to tap the sequence as few errors as possible Task 2: Participants perform a motor adaptation task requiring scrolling a trackball to superimpose a geometric shape on another one, strictly similar but presented from another angle, as fast as possible.

Practice session

Intervention Type OTHER

Participants of the Day group perform a block of motor imagery practice of the two motor tasks.

MEG recordings (Post-test)

Intervention Type OTHER

Participants perform the two motor tasks in the MEG (post-test, strictly similar to the pre-test)

MRI

Intervention Type OTHER

The registration of the brain anatomy of each participant will be done by MRI 3D / T the week before the first experimental session.

Interventions

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Imagery and Sleep questionnaires

Participants complete a motor imagery questionnaire to assess their ability to form vivid mental images, as well as sleep questionnaires to control the quality of their sleep

Intervention Type OTHER

MEG recordings (pre-test)

Participants of the Day group perform two motor tasks (a finger sequential motor task and an adaptation motor task using a trackball) in the MEG, during a pre-test (Day 1 - 9h).

Task 1: Participants perform an 8-digit motor sequential task where each finger (except the thumb) is used twice. Performance is assessed by using a 4-keys keyboard. Participants are required to keep their fingers on the keys to minimize amplitude are instructed to tap the sequence as few errors as possible Task 2: Participants perform a motor adaptation task requiring scrolling a trackball to superimpose a geometric shape on another one, strictly similar but presented from another angle, as fast as possible.

Intervention Type OTHER

Practice session

Participants of the Day group perform a block of motor imagery practice of the two motor tasks.

Intervention Type OTHER

MEG recordings (Post-test)

Participants perform the two motor tasks in the MEG (post-test, strictly similar to the pre-test)

Intervention Type OTHER

MRI

The registration of the brain anatomy of each participant will be done by MRI 3D / T the week before the first experimental session.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy right-handed persons without neurologic disease
* Persons having signed informed consent for a neuroimagery study

Exclusion Criteria

* Persons under curatorship or any administrative/judicial measure
* Participants refusing to be informed of the results of the experiment
* Pregnant women
* Participants with contraindications to the MEG examination: head size, presence of a neurostimulator, steel pivot for the root canal, metallic fragments, ear implants, metal screws in the body or mouth.
* Persons using a pacemaker, insulin pump, or working regularly with iron filings
* Claustrophobic persons
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alain Nicolas, MD

Role: PRINCIPAL_INVESTIGATOR

CH le Vinatier

Locations

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CH le Vinatier

Bron, , France

Site Status

Countries

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France

References

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Di Rienzo F, Debarnot U, Daligault S, Delpuech C, Doyon J, Guillot A. Brain plasticity underlying sleep-dependent motor consolidation after motor imagery. Cereb Cortex. 2023 Nov 27;33(23):11431-11445. doi: 10.1093/cercor/bhad379.

Reference Type BACKGROUND
PMID: 37814365 (View on PubMed)

Other Identifiers

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69HCL16_0676

Identifier Type: -

Identifier Source: org_study_id

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