A Trial Comparing Deep Versus Moderate Neuromuscular Block

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-04-30

Study Completion Date

2016-02-29

Brief Summary

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Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation. Low pressure pneumoperitoneum can decrease postoperative pain and therefore also concomitant use of opioids.

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Detailed Description

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However low pressure pneumoperitoneum can also decrease peri-operative conditions. In this trial the researchers will investigate whether peri-operative conditions during low pressure pneumoperitoneum can be optimized by the use of deep neuromuscular block.

Conditions

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Nephrostomy; Complications Pneumoperitoneum Observation of Neuromuscular Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Deep neuromsucular block

Deep neuromuscular block and low pressure pneumoperitoneum

Group Type EXPERIMENTAL

Deep neuromsucular block

Intervention Type OTHER

Deep or standard neuromuscular block

Standard neuromuscular block

Standard neuromuscular block and low pressure pneumoperitoneum

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Deep neuromsucular block

Deep or standard neuromuscular block

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* obtained informed consent
* age over 18 years

Exclusion Criteria

* chronic use of analgesics or psychotropic drugs
* use of non-steroidal anti-inflammatory drugs shorter than 5 days before surgery
* known or suspect allergy to rocuronium or sugammadex
* significant liver or renal dysfunction
* pregnant or breastfeeding

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No