Comparison of Perioperative Analgesic Efficacy of Femoral Nerve Block, Adductor Canal Block and 4in1 Block

NCT ID: NCT05643040

Last Updated: 2025-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-01

Study Completion Date

2025-06-30

Brief Summary

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Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to placebo or patient-controlled analgesia (PCA). In addition, opioid-related side effects such as postoperative nausea, vomiting, pruritus, sedation, and respiratory depression are less. Therefore, interest in regional blocks such as femoral, sciatic, adductor, combined femoral, and sciatic is increasing. The knee joint is innervated by various nerves (genicular nerves) from the femoral, obturator, and sciatic nerves, and a comprehensive but simple technique is needed for postoperative analgesia. Complete and comprehensive postoperative analgesia was possible with this block, a simple single injection technique. The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block, and 4in1 block in patients who will undergo knee surgery.

Detailed Description

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Conditions

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Block Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Group I: Femoral nerve block Group II: Adductor canal block Group III: 4in1 block
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

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femoral nerve block

To evaluate the intraoperative analgesia effectiveness of femoral nerve block in patients who will have knee surgery.

Group Type EXPERIMENTAL

femoral nerve block

Intervention Type OTHER

To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.

adductor canal block

To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.

Group Type EXPERIMENTAL

adductor canal block

Intervention Type OTHER

To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.

4in1 block

To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.

Group Type EXPERIMENTAL

4in1 block

Intervention Type OTHER

To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.

Interventions

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femoral nerve block

To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.

Intervention Type OTHER

adductor canal block

To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.

Intervention Type OTHER

4in1 block

To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients between the ages of \>18
* undergone knee surgery
* American Society of Anesthesiologists (ASA) classification I-III group.

Exclusion Criteria

* Patients who do not want to participate in the study coagulopathy peripheral neuropathy local anesthetic drug allergy chronic opioid users anticoagulant users pregnant patients
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Diskapi Yildirim Beyazit Education and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Funda Atar

Diskapi Yildirim Beyazit Education and Research Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Medical Science, Yıldırım Beyazıt Training and Research Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, Sage D, Futter M, Saville G, Clark T, MacMahon S. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ. 2000 Dec 16;321(7275):1493. doi: 10.1136/bmj.321.7275.1493.

Reference Type BACKGROUND
PMID: 11118174 (View on PubMed)

Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for total knee arthroplasty: Ultrasound guided single injection modified 4 in 1 block. J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):261-264. doi: 10.4103/joacp.JOACP_260_19. Epub 2020 Jun 15.

Reference Type BACKGROUND
PMID: 33013045 (View on PubMed)

Other Identifiers

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06/06/2022 139/13

Identifier Type: -

Identifier Source: org_study_id

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