Combined PENG and LFCN Block for Total Hip Arthroplasty

NCT ID: NCT04996290

Last Updated: 2021-08-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-01

Study Completion Date

2020-10-01

Brief Summary

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A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block. The results will be compared to a control group that is solely treated with intravenous analgesia. This technique aims to provide improved pain scores after surgery without interference of revalidation.

Detailed Description

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Conditions

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Anesthesia, Conduction Pain, Postoperative Arthroplasty, Replacement, Hip

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

prospective randomized controlled trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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PENG + LFCN block

The participants in this group received a combined regional technique just before surgery:

* Pericapsular nerve group (PENG) block
* Lateral femoral cutaneus nerve (LFCN) block

Group Type ACTIVE_COMPARATOR

PENG + LFCN block

Intervention Type PROCEDURE

Regional anesthesia technique

Ropivacaine injection

Intervention Type DRUG

Local anesthetic used for peripheral nerve block.

No regional anesthesia

Control group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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PENG + LFCN block

Regional anesthesia technique

Intervention Type PROCEDURE

Ropivacaine injection

Local anesthetic used for peripheral nerve block.

Intervention Type DRUG

Other Intervention Names

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pericapsular nerve group block lateral femoral cutaneous nerve block ropivacaine 0.375%

Eligibility Criteria

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Inclusion Criteria

* adult patients who underwent a primary total hip replacement under general anesthesia

Exclusion Criteria

* insulin dependent diabetes mellitus
* chronic pain
* severe dementia or mental retardation
* allergy to local anesthetics
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Antwerp

OTHER

Sponsor Role lead

Responsible Party

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Lennert De Schrijver

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yzabel Vandevivere, MD

Role: PRINCIPAL_INVESTIGATOR

AZ Monica

Locations

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AZ Monica

Deurne, , Belgium

Site Status

Countries

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Belgium

References

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Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.

Reference Type BACKGROUND
PMID: 30063657 (View on PubMed)

Morrison C, Brown B, Lin DY, Jaarsma R, Kroon H. Analgesia and anesthesia using the pericapsular nerve group block in hip surgery and hip fracture: a scoping review. Reg Anesth Pain Med. 2021 Feb;46(2):169-175. doi: 10.1136/rapm-2020-101826. Epub 2020 Oct 27.

Reference Type BACKGROUND
PMID: 33109730 (View on PubMed)

Wainwright TW, Gill M, McDonald DA, Middleton RG, Reed M, Sahota O, Yates P, Ljungqvist O. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Acta Orthop. 2020 Feb;91(1):3-19. doi: 10.1080/17453674.2019.1683790. Epub 2019 Oct 30.

Reference Type BACKGROUND
PMID: 31663402 (View on PubMed)

Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for hip surgeries, PENG block with LFCN block. Reg Anesth Pain Med. 2019 Mar 28:rapm-2019-100454. doi: 10.1136/rapm-2019-100454. Online ahead of print. No abstract available.

Reference Type BACKGROUND
PMID: 30923252 (View on PubMed)

Hojer Karlsen AP, Geisler A, Petersen PL, Mathiesen O, Dahl JB. Postoperative pain treatment after total hip arthroplasty: a systematic review. Pain. 2015 Jan;156(1):8-30. doi: 10.1016/j.pain.0000000000000003.

Reference Type BACKGROUND
PMID: 25599296 (View on PubMed)

Other Identifiers

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B3002020000032

Identifier Type: -

Identifier Source: org_study_id

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