Bed-rest, Muscle Mass and Insulin Sensitivity

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-30

Brief Summary

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In the present study, the effects of 7 days of bed rest on muscle mass, muscle fiber characteristics and insulin sensitivity will be determined.

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Detailed Description

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Conditions

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Disuse Atrophy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Bed rest

One week of bed rest.

Group Type EXPERIMENTAL

Bed rest

Intervention Type BEHAVIORAL

Interventions

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Bed rest

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Male
* Aged from 18-35 years
* 18.5 \< BMI \< 30 kg/m2

Exclusion Criteria

* Smoking
* Performing regular resistance training (3+ times per week, carrying out progressive training) in the previous 6 months
* Hypertension (according to WHO criteria) and/or cardiovascular disease
* Any back/leg/knee/neck/postural complaints
* Use of any prescribed medication
* Type 2 diabetes mellitus
* Any family history of thrombosis
* All co-morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthritis, spasticity/rigidity, all neurological disorders and paralysis).
* Myocardial infarction within the last 3 years
* Use of anti-coagulants

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes