Mechanism of Action of Milk and Its Components on Glycemic Control in Healthy Young Men

NCT ID: NCT01812967

Last Updated: 2013-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Brief Summary

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The investigators hypothesize that the physiological effects of milk on satiety and glycemic control are mediated by the interaction between its macronutrient components by both insulin-dependent and independent mechanisms.

Detailed Description

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Conditions

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Glycemic Control Gastrointestinal Hormone Response Healthy Young Men

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Interventions

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Milk Fat

Intervention Type DIETARY_SUPPLEMENT

Milk Protein

Intervention Type DIETARY_SUPPLEMENT

Lactose

Intervention Type DIETARY_SUPPLEMENT

Whole milk (3.25% M.F.(

Commercially available milk from the grocery store

Intervention Type OTHER

Simulated Milk Beverage

Added lactose + fat + protein together to form a mixture

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy young men
* 20-30 years of age
* BMI: 20-24.9 kg/m2

Exclusion Criteria

* Smoking
* Dieting
* Skipping breakfast
* Lactose intolerance or allergies to milk
* Taking medications that may affect glucose metabolism or appetite
* Diabetes (fasting blood glucose ≥ 7.0 mmol/L) or other metabolic diseases
Minimum Eligible Age

20 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Toronto

OTHER

Sponsor Role lead

Responsible Party

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G. Harvey Anderson

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Toronto

Toronto, Ontario, Canada

Site Status

Countries

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Canada

References

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Panahi S, El Khoury D, Kubant R, Akhavan T, Luhovyy BL, Goff HD, Anderson GH. Mechanism of action of whole milk and its components on glycemic control in healthy young men. J Nutr Biochem. 2014 Nov;25(11):1124-1131. doi: 10.1016/j.jnutbio.2014.07.002. Epub 2014 Jul 31.

Reference Type DERIVED
PMID: 25167977 (View on PubMed)

Other Identifiers

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Milk Components Study

Identifier Type: -

Identifier Source: org_study_id

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