Genetic Information and Dietary Intake Behaviour

NCT ID: NCT01353014

Last Updated: 2014-07-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

138 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2012-09-30

Brief Summary

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This study's primary objective is to determine if providing individuals with personal genetic information impacts dietary intake behaviour. Specifically, the investigators will be examining whether providing dietary advice based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium will impact the intake of these dietary components. The study hypothesis is that providing dietary advice based on genetics will impact dietary behaviour to a greater extent than general dietary recommendations.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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Dietary advice with genetic information

This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genetic information.

Group Type EXPERIMENTAL

Dietary advice with genetic information

Intervention Type OTHER

This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium.

General dietary recommendations

This group will receive general dietary recommendations for caffeine, vitamin C, sugar and sodium from recognized health institutions (caffeine: Health Canada; sugar: the World Health Organization; vitamin C and sodium: the Institute of Medicine).

Group Type ACTIVE_COMPARATOR

General dietary recommendations

Intervention Type OTHER

This group will receive general dietary recommendations from recognized health organizations for caffeine, vitamin C, sugar and sodium, with no genetic information.

Interventions

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Dietary advice with genetic information

This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium.

Intervention Type OTHER

General dietary recommendations

This group will receive general dietary recommendations from recognized health organizations for caffeine, vitamin C, sugar and sodium, with no genetic information.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 20-35 year old participants from the Toronto Nutrigenomics and Health Study

Exclusion Criteria

* pregnancy or nursing
* vitamin C supplement users
* caffeine intake \< 100 mg/day
* total sugars intake \< 10% energy
* sodium intake \< 1500 mg/day
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Advance Foods and Materials Network

OTHER

Sponsor Role collaborator

University of Toronto

OTHER

Sponsor Role lead

Responsible Party

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Ahmed El-Sohemy

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed El-Sohemy, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Toronto

Locations

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University of Toronto

Toronto, Ontario, Canada

Site Status

Countries

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Canada

References

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Nielsen DE, El-Sohemy A. Disclosure of genetic information and change in dietary intake: a randomized controlled trial. PLoS One. 2014 Nov 14;9(11):e112665. doi: 10.1371/journal.pone.0112665. eCollection 2014.

Reference Type DERIVED
PMID: 25398084 (View on PubMed)

Other Identifiers

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AElSohemy

Identifier Type: -

Identifier Source: org_study_id

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