Glycemic Index and Polyphenol Bioavailability of Potatoes

NCT ID: NCT01053793

Last Updated: 2011-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes Insulin Resistance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Glucose Standard

Group Type ACTIVE_COMPARATOR

Glycemic response to different varieties of potatoes

Intervention Type OTHER

the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard

Potato Variety

Group Type EXPERIMENTAL

Glycemic response to different varieties of potatoes

Intervention Type OTHER

the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Glycemic response to different varieties of potatoes

the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Purple potato Red potato White potato Yellow potaot

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* healthy, non-smoker on no medication
* normal glucose tolerance
* willing to have a catheter inserted in forearm

Exclusion Criteria

* abnormal glucose tolerance
* abnormal BMI
* on medication for a chronic disorder
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

NETWORK

Sponsor Role collaborator

Guelph Food Research Centre

OTHER_GOV

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Agriculture and Agri-Food Canada - Guelph Food Research Centre

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Dan Ramdath, PhD

Role: PRINCIPAL_INVESTIGATOR

Agriculture and Agri-Food Canada

Maggie Laidlaw, PhD

Role: STUDY_DIRECTOR

Nutracource Diagnostics Inc

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Nutrasource Diagnostic Inc

Guelph, Ontario, Canada

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada

References

Explore related publications, articles, or registry entries linked to this study.

Wolever TM, Brand-Miller JC, Abernethy J, Astrup A, Atkinson F, Axelsen M, Bjorck I, Brighenti F, Brown R, Brynes A, Casiraghi MC, Cazaubiel M, Dahlqvist L, Delport E, Denyer GS, Erba D, Frost G, Granfeldt Y, Hampton S, Hart VA, Hatonen KA, Henry CJ, Hertzler S, Hull S, Jerling J, Johnston KL, Lightowler H, Mann N, Morgan L, Panlasigui LN, Pelkman C, Perry T, Pfeiffer AF, Pieters M, Ramdath DD, Ramsingh RT, Robert SD, Robinson C, Sarkkinen E, Scazzina F, Sison DC, Sloth B, Staniforth J, Tapola N, Valsta LM, Verkooijen I, Weickert MO, Weseler AR, Wilkie P, Zhang J. Measuring the glycemic index of foods: interlaboratory study. Am J Clin Nutr. 2008 Jan;87(1):247S-257S. doi: 10.1093/ajcn/87.1.247S.

Reference Type BACKGROUND
PMID: 18175765 (View on PubMed)

Ramdath DD, Isaacs RL, Teelucksingh S, Wolever TM. Glycaemic index of selected staples commonly eaten in the Caribbean and the effects of boiling v. crushing. Br J Nutr. 2004 Jun;91(6):971-7. doi: 10.1079/bjn20041125.

Reference Type BACKGROUND
PMID: 15182400 (View on PubMed)

Wolever TM, Vorster HH, Bjorck I, Brand-Miller J, Brighenti F, Mann JI, Ramdath DD, Granfeldt Y, Holt S, Perry TL, Venter C, Xiaomei Wu. Determination of the glycaemic index of foods: interlaboratory study. Eur J Clin Nutr. 2003 Mar;57(3):475-82. doi: 10.1038/sj.ejcn.1601551.

Reference Type BACKGROUND
PMID: 12627186 (View on PubMed)

Wolever TM, Isaacs RL, Ramdath DD. Lower diet glycaemic index in African than South Asian men in Trinidad and Tobago. Int J Food Sci Nutr. 2002 Jul;53(4):297-303. doi: 10.1080/09637480220138142.

Reference Type BACKGROUND
PMID: 12090025 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

GFRC 09-11-004

Identifier Type: OTHER

Identifier Source: secondary_id

09-11-004

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Genetic Information and Dietary Intake Behaviour
NCT01353014 COMPLETED EARLY_PHASE1