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Glucose Response From Antioxidant Rich Potato Chips

NCT ID: NCT02927015

Last Updated: 2016-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-31

Study Completion Date

2016-06-30

Brief Summary

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Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.

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Detailed Description

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Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.

Conditions

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Glycemic Response

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Purple Majesty potato chips

Purple Majesty potato chips

Group Type EXPERIMENTAL

Purple Majesty potato chips

Intervention Type OTHER

Purple Majesty potato chips

Mountain Rose potato chips

Mountain Rose potato chips

Group Type EXPERIMENTAL

Mountain Rose potato chips

Intervention Type OTHER

Mountain Rose potato chips

White potato chips

White potato chips

Group Type EXPERIMENTAL

White potato chips

Intervention Type OTHER

White potato chips

Crackers

Crackers

Group Type EXPERIMENTAL

Crackers

Intervention Type OTHER

Crackers

Interventions

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Purple Majesty potato chips

Purple Majesty potato chips

Intervention Type OTHER

Mountain Rose potato chips

Mountain Rose potato chips

Intervention Type OTHER

White potato chips

White potato chips

Intervention Type OTHER

Crackers

Crackers

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* BMI 18-25 non-smoker

Exclusion Criteria

* BMI outside 18-25 smoker previous gastrointestinal disease or other disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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PepsiCo Global R&D

INDUSTRY

Sponsor Role collaborator

Purdue University

OTHER

Sponsor Role lead

Responsible Party

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Richard Mattes

Prof. Nutrition Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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055-043

Identifier Type: -

Identifier Source: org_study_id

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