Bioavailability of Potassium From Potatoes and Potassium Gluconate
NCT ID: NCT01881295
Last Updated: 2018-05-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2013-03-01
2014-12-31
Brief Summary
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Detailed Description
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During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
SINGLE
Study Groups
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Placebo control
Subjects will consume tablets containing no potassium in addition to a basal diet containing 2336 mg potassium
Placebo control
Low dose potassium gluconate
Subjects will consume 720 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
Low dose potassium gluconate
Medium dose potassium gluconate
Subjects will consume 1440 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
Medium dose potassium gluconate
High dose potassium gluconate
Subjects will consume 2160 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
High dose potassium gluconate
Low dose potato
Subjects will consume 720 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
Low dose potato
Medium dose potato
Subjects will consume 1440 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
Medium dose potato
High dose potato
Subjects will consume 2160 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
High dose potato
High dose French fries
Subjects will consume 2160 mg potassium in the form of french fries daily in addition to a basal diet containing 2336 mg potassium
High dose French fries
Basal diet control
Subjects will consume a basal diet containing 2336 mg potassium daily
Basal diet control
Interventions
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Placebo control
Low dose potassium gluconate
Medium dose potassium gluconate
High dose potassium gluconate
Low dose potato
Medium dose potato
High dose potato
High dose French fries
Basal diet control
Eligibility Criteria
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Inclusion Criteria
* Normotensive men and women
* Aged 20-60 years
* BMI of 15-35
Exclusion Criteria
* Medication known to affect electrolyte metabolism or contain high levels of potassium or sodium
* smoke cigarettes or use illegal drugs
* Hypertension or hypotension
* Diseases known to affect potassium metabolism
* Pregnant
* Allergic to nuts
20 Years
60 Years
ALL
Yes
Sponsors
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Alliance for Potato Research and Education
OTHER
Purdue University
OTHER
Responsible Party
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Berdine Martin
Research Scientist
Principal Investigators
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Connie M Weaver, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Purdue University
Berdine R Martin, Ph.D.
Role: STUDY_DIRECTOR
Purdue University
Locations
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Purdue University
West Lafayette, Indiana, United States
Countries
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References
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Macdonald-Clarke CJ, Martin BR, McCabe LD, McCabe GP, Lachcik PJ, Wastney M, Weaver CM. Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial. Am J Clin Nutr. 2016 Aug;104(2):346-53. doi: 10.3945/ajcn.115.127225. Epub 2016 Jul 13.
Other Identifiers
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1301013174
Identifier Type: -
Identifier Source: org_study_id
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