Lentils as a Functional Food to Improve Glucose and Decrease Cardiovascular Risk
NCT ID: NCT01562171
Last Updated: 2014-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
102 participants
INTERVENTIONAL
2012-03-31
2014-09-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
NONE
Study Groups
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Cooked Lentils
The study group will be asked to consume food items containing one serving of (0.3 cups) of cooked lentils per day for the first 5 days, followed by one serving of (0.6 cups) of cooked lentils per day 5 times per week (equivalent of 3 cups cooked lentils per week) for the remainder of the 12-week schedule.
Cooked Lentils
Consume food items containing one serving of (0.3 cups) of cooked lentils per day for the first 5 days, followed by one serving of (0.6 cups) of cooked lentils per day 5 times per week (equivalent of 3 cups cooked lentils per week) for the remainder of the 12-week schedule.
Potato-Based Foods
The control group will be asked to consume one serving per day of potato-based foods in matrices similar to those containing lentils in the same 12-week schedule, including the smaller serving size for the first 5 days.
Potato-Based Foods
Control - Consumption of one serving per day of potato-based foods in matrices similar to those containing lentils in the same 12-week schedule, including the smaller serving size for the first 5 days.
Interventions
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Cooked Lentils
Consume food items containing one serving of (0.3 cups) of cooked lentils per day for the first 5 days, followed by one serving of (0.6 cups) of cooked lentils per day 5 times per week (equivalent of 3 cups cooked lentils per week) for the remainder of the 12-week schedule.
Potato-Based Foods
Control - Consumption of one serving per day of potato-based foods in matrices similar to those containing lentils in the same 12-week schedule, including the smaller serving size for the first 5 days.
Eligibility Criteria
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Inclusion Criteria
* Body Mass Index of ≤40 kg/m2 and ≥23 kg/m2 if Asian or ≥25 kg/m2 if non-Asian;
* Waist circumference ≥94 cm for males and ≥80 cm for females of Asian ethnicity,and ≥102 cm for males and ≥88 cm of non-Asian ethnicity;
* Fasting plasma glucose \<7 mmol/L;
* Fasting triglycerides \<4.00 mmol/L and LDL-cholesterol \>2.50 mmol/L and \<5.00 mmol/L;
* Must be on a stable regime for the past 3 months if taking medications to treat hypertension or if taking vitamin and mineral/dietary/herbal supplements;
* Stable body weight (±3 kg) for the past 3 months
Exclusion Criteria
* High pulse consumption (≥2 servings per week);
* Presence of liver disease (aspartate transaminase \>2 times Upper Normal Limit), renal insufficiency (creatinine \>1.5 times Upper Normal Limit); inflammatory bowel disease or other gastrointestinal disorders influencing gastrointestinal motility or nutrient absorption;
* Use of medication which influence carbohydrate metabolism (i.e., steroids), or medications used to treat diabetes or to lower blood lipids, or any active medical or surgical conditions within the past 3 months;
* Conditions or medications which are likely to increase the risk to the participants or study personnel, or to reduce the ability of the participant to comply with the protocol, or affect the results;
* History of gastrointestinal reactions or allergies to lentils or potato-based foods, or to one or more ingredients in the study foods which significantly limits the number of study foods that can be consumed.
30 Years
75 Years
ALL
No
Sponsors
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Glycemic Index Laboratories, Inc
INDUSTRY
Agriculture and Agri-Food Canada
OTHER_GOV
Saskatchewan Pulse Growers
OTHER
University of Manitoba
OTHER
Responsible Party
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Dr. Carla Taylor
Professor, Department of Human Nutritional Sciences
Principal Investigators
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Carla Taylor, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Manitoba
Locations
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I.H. Asper Clinical Research Institute
Winnipeg, Manitoba, Canada
Glycemic Index Laboratories, Incorporated
Toronto, Ontario, Canada
Countries
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References
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Pauls SD, Du Y, Clair L, Winter T, Aukema HM, Taylor CG, Zahradka P. Impact of Age, Menopause, and Obesity on Oxylipins Linked to Vascular Health. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):883-897. doi: 10.1161/ATVBAHA.120.315133. Epub 2020 Dec 31.
Related Links
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Canadian Centre for Agri-Food Research in Health \& Medicine (website)
Other Identifiers
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B2012:010
Identifier Type: -
Identifier Source: org_study_id