MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study

NCT ID: NCT00956631

Last Updated: 2013-04-04

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

78 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-07-31

Study Completion Date

2012-04-30

Brief Summary

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This is a multi-center, prospective, clinical study to assess the clinical application and outcomes of MILD® Interlaminar Decompression in patients with symptomatic lumbar spinal stenosis.

Detailed Description

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Conditions

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Lumbar Spinal Stenosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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interlaminar decompression

Commercially available product (mild® Device Kit) used to perform interlaminar decompression

Group Type OTHER

Interlaminar Decompression

Intervention Type PROCEDURE

The MILD® devices used in this study are specialized surgical instruments intended to be used to perform percutaneous lumbar decompression.

Interventions

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Interlaminar Decompression

The MILD® devices used in this study are specialized surgical instruments intended to be used to perform percutaneous lumbar decompression.

Intervention Type PROCEDURE

Other Intervention Names

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mild® Device Kit percutaneous decompression

Eligibility Criteria

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Inclusion Criteria

* Symptomatic Lumbar Spinal Stenosis (LSS) primarily caused by dorsal element hypertrophy.
* Prior failure of conservative therapy.
* Radiologic evidence of LSS (L3-L5), Ligamentum flavum \> 2.5mm, confirmed by pre-op MRI and/or CT.
* Central canal cross sectional area ≤ 100 square mm.
* Anterior listhesis ≤ 5.0mm.
* Able to walk at least 10 feet unaided before being limited by pain.
* Available to complete 12 weeks of follow-up.
* Consistent with the intended labeling statement for use.
* Able to use all package components to perform the procedure.
* A signed Informed Consent Form is obtained from the patient.

Exclusion Criteria

* Prior surgery at intended treatment level.
* History of recent spinal fractures with concurrent pain symptoms.
* Disabling back or leg pain from causes other than LSS (e.g. acute compression fracture, metabolic neuropathy, or vascular claudication symptoms, etc.).
* Significant / symptomatic disk protrusion or osteophyte formation.
* Excessive / symptomatic facet hypertrophy.
* Bleeding disorders and/or current use of anti-coagulants.
* Use of acetylsalicylic acid (ASA) and/or non-steroidal anti-inflammatory drug (NSAID) within 5 days of treatment.
* Epidural steroids within prior three weeks.
* Inability of the patient to lie prone for any reason with anesthesia support (e.g. chronic obstructive pulmonary disease (COPD), obesity, etc.).
* Any potential wound healing pathologies that may compromise outcomes, including diabetes, excessive smoking history, cancer, connective tissue diseases, recent spine radiation and severe COPD.
* Dementia and/or inability to give informed consent.
* Pregnancy.
* Intended treatment that is defined by the product labeling contraindications.
* On Workman's Compensation or considering litigation associated with back pain.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vertos Medical, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David Caraway, MD

Role: PRINCIPAL_INVESTIGATOR

The Center for Pain Relief Tri-State, PLLC

Bohdan W Chopko, MD

Role: PRINCIPAL_INVESTIGATOR

MedCentral Health System

Locations

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NEA Clinic

Jonesboro, Arkansas, United States

Site Status

UCLA

Los Angeles, California, United States

Site Status

Napa Pain Institute

Napa, California, United States

Site Status

Scripps, Division of Orthopedic Surgery

San Diego, California, United States

Site Status

UCSD

San Diego, California, United States

Site Status

Your Pain Care

Temecula, California, United States

Site Status

Coastal Orthopedics & Sports Medicine

Bradenton, Florida, United States

Site Status

South Florida Spine Institute

Miami Beach, Florida, United States

Site Status

The Spine Center

Baltimore, Maryland, United States

Site Status

Rainer Vogel, MD LTD

Henderson, Nevada, United States

Site Status

Lab2Marche, LLC

Las Vegas, Nevada, United States

Site Status

MedCentral Health System

Mansfield, Ohio, United States

Site Status

Orthopedic Associates of the Greater Lehigh Valley

Easton, Pennsylvania, United States

Site Status

Countries

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United States

References

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Chopko B, Caraway DL. MiDAS I (mild Decompression Alternative to Open Surgery): a preliminary report of a prospective, multi-center clinical study. Pain Physician. 2010 Jul-Aug;13(4):369-78.

Reference Type DERIVED
PMID: 20648206 (View on PubMed)

Other Identifiers

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MiDAS I

Identifier Type: -

Identifier Source: org_study_id

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