Complex Problem Solving Training in Schizophrenic Patients

NCT ID: NCT00507988

Last Updated: 2009-05-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

91 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-08-31

Study Completion Date

2009-02-28

Brief Summary

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The primary purpose of the study is to assess whether a planning and problem-solving training is more effective in improving work therapy performance in patients with schizophrenia than traditional training programs addressing basic cognitive functions.

Detailed Description

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In patients with schizophrenia, cognitive deficits often lead to an impairment in daily life. This observation has led to the development of cognitive training packages aiming a improving these deficits. However, it is far from clear which level of cognitive functioning provides the best target for cognitive interventions. Traditionally, training has aimed a basic cognitive functions like attention and memory. In the present study we aim at a higher-level of function, namely planning and problem-solving skills, which are trained using the software package Plan-A-Day. The primary hypothesis is that complex problem solving training improved functional capacity more than traditional training programs addressing basic cognitive function.

Conditions

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Schizophrenia Schizoaffective Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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A

Complex Problem Solving Training

Group Type EXPERIMENTAL

Complex Problem Solving Training

Intervention Type BEHAVIORAL

10 sessions of 45 minutes complex problem solving training over 3 weeks (including 30 minutes of computerized planning and problem-solving training with Plan-A-Day and 15 minutes group session for transfer to everyday situations)

B

Basic Cognitive Training

Group Type ACTIVE_COMPARATOR

Basic Cognitive Training

Intervention Type BEHAVIORAL

10 sessions over 3 weeks of 45 min basic cognitive training (including 45 min computerized training of attention, processing speed, memory)

Interventions

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Complex Problem Solving Training

10 sessions of 45 minutes complex problem solving training over 3 weeks (including 30 minutes of computerized planning and problem-solving training with Plan-A-Day and 15 minutes group session for transfer to everyday situations)

Intervention Type BEHAVIORAL

Basic Cognitive Training

10 sessions over 3 weeks of 45 min basic cognitive training (including 45 min computerized training of attention, processing speed, memory)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients with schizophrenic or schizoaffective Disorder (DSM IV)
* Remitted positive symptoms (PANSS positive all ≤ 4), clinical stability
* Native German speaker
* Verbal IQ \> 80
* Visual acuity normal or corrected to normal

Exclusion Criteria

* Concurrent Axis-I disorder
* Drug abuse during last 2 months
* Neurological or medical conditions potentially affecting cognition
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Federal Ministry of Education and Research

OTHER_GOV

Sponsor Role collaborator

Heidelberg University

OTHER

Sponsor Role lead

Responsible Party

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University Hospital Heidelberg

Principal Investigators

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Matthias Weisbrod, MD

Role: PRINCIPAL_INVESTIGATOR

SRH Klinikum Karlsbad-Langensteinbach, Department of Psychiatry

Locations

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SRH Klinikum Karlsbad-Langensteinbach

Karlsbad, , Germany

Site Status

Countries

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Germany

References

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Rodewald K, Rentrop M, Holt DV, Roesch-Ely D, Backenstrass M, Funke J, Weisbrod M, Kaiser S. Planning and problem-solving training for patients with schizophrenia: a randomized controlled trial. BMC Psychiatry. 2011 Apr 28;11:73. doi: 10.1186/1471-244X-11-73.

Reference Type DERIVED
PMID: 21527028 (View on PubMed)

Other Identifiers

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01GW0630

Identifier Type: -

Identifier Source: org_study_id

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