Resistance Exercise in Severe Knee Osteoarthritis

NCT ID: NCT06664905

Last Updated: 2024-10-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-10

Study Completion Date

2023-12-05

Brief Summary

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This study aim to evaluate pain after different resistance training protocols (placebo, 4 sets of 10RM, 8 sets of 10 RM and 12 sets of 10RM) in patients with severe knee osteoarthritis.

Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Placebo

control, with no exercise

Group Type ACTIVE_COMPARATOR

Placebo

Intervention Type OTHER

No exercise

4 sets

4 sets of 10RM of knee extensions

Group Type EXPERIMENTAL

Resistance Exercise

Intervention Type OTHER

10 Repetition Maximum (RM)

8 sets

8 sets of 10RM of knee extensions

Group Type EXPERIMENTAL

Resistance Exercise

Intervention Type OTHER

10 Repetition Maximum (RM)

12 sets

12 sets of 10RM of knee extensions

Group Type EXPERIMENTAL

Resistance Exercise

Intervention Type OTHER

10 Repetition Maximum (RM)

Interventions

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Resistance Exercise

10 Repetition Maximum (RM)

Intervention Type OTHER

Placebo

No exercise

Intervention Type OTHER

Other Intervention Names

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Control

Eligibility Criteria

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Inclusion Criteria

* men and women at least 55 years old
* diagnosed with severe knee OA
* scheduled for unilateral Total Knee Arthroplasty (TKA) surgery

Exclusion Criteria

* pain in the contralateral (non-studied) limb (maximum ≥80 of 100 mm on a visual analog scale (VAS) during daily activities)
* another hip or knee joint replacement in the previous year
* any medical condition in which exercise was contraindicated
* participated in exercise programs (\>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study
* history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of study tasks
Minimum Eligible Age

55 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Valencia

OTHER

Sponsor Role lead

Responsible Party

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José Casaña Granell

Head of the Physiotherapy Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Clinic Universitary Hospital of Valencia

Valencia, , Spain

Site Status

Countries

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Spain

Other Identifiers

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OA-2023

Identifier Type: -

Identifier Source: org_study_id

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