Exercise With Blood Flow Restriction in Knee Osteoarthritis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-21

Study Completion Date

2022-05-20

Brief Summary

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The purpose of this study is to evaluate the neuromuscular responses, pain intensity and rate of perceived exertion in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with blood flow restriction at different levels of arterial occlusion pressure.

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Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Placebo

Knee extensions with 30% 1RM and no occlusion pressure.

Group Type ACTIVE_COMPARATOR

BFR resistance exercise

Intervention Type OTHER

4 sets (30, 15, 15, 15 reps).

BFR at 40% AOP

Knee extensions with 30% 1RM and BFR at 40% AOP.

Group Type EXPERIMENTAL

BFR resistance exercise

Intervention Type OTHER

4 sets (30, 15, 15, 15 reps).

BFR at 80% AOP

Knee extensions with 30% 1RM and BFR at 80% AOP.

Group Type EXPERIMENTAL

BFR resistance exercise

Intervention Type OTHER

4 sets (30, 15, 15, 15 reps).

Interventions

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BFR resistance exercise

4 sets (30, 15, 15, 15 reps).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* men and women above 55 years old.
* diagnosed with severe knee osteoarthritis.
* scheduled for unilateral TKA surgery in a local hospital during 2021- 2022.

Exclusion Criteria

* pain in the contralateral limb (maximum pain, ≥80 of 100 mm on a VAS during daily activities).
* another hip or knee joint replacement in the previous year.
* any medical condition in which exercise was contraindicated.
* participated in exercise programs (\>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study.
* history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of dual tasks.

Minimum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No