A Study to Compare Two Rehabilitation Protocols for Knee Osteoarthritis
NCT ID: NCT05728827
Last Updated: 2024-08-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
70 participants
INTERVENTIONAL
2023-03-15
2026-02-28
Brief Summary
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Participants will be divided as follows:
Intervention group: anti-gravity treadmill combined with blood flow restriction Control group: anti-gravity treadmill Both groups will also undergo a standardized knee Osteoarthritis management through an aerobic and strength program.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Anti-gravity treadmill + Blood Flow Restriction training
Blood flow restriction training + Anti-gravity treadmill
Blood flow restriction training is administered via straps applied to the proximal limb with the possibility to adjust the applied occlusion pressure in order to prevent venous return leaving the arterial flow partially free. The consequent blood pooling causes a reduction in tissue saturation with oxidative stress and an increased growth factors secretion. The intervention will be applied while walking/running on the anti-gravity treadmill.
Anti-gravity treadmill
Anti-gravity treadmill
The intervention will be applied walking/running on the anti-gravity treadmill.
Interventions
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Blood flow restriction training + Anti-gravity treadmill
Blood flow restriction training is administered via straps applied to the proximal limb with the possibility to adjust the applied occlusion pressure in order to prevent venous return leaving the arterial flow partially free. The consequent blood pooling causes a reduction in tissue saturation with oxidative stress and an increased growth factors secretion. The intervention will be applied while walking/running on the anti-gravity treadmill.
Anti-gravity treadmill
The intervention will be applied walking/running on the anti-gravity treadmill.
Eligibility Criteria
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Inclusion Criteria
* Patients with knee OA diagnosed by a medical doctor with a radiological confirmation
* Patients able to provide informed consent and follow all the study procedures as indicated by the protocol
* Informed Consent as documented by signature
Exclusion Criteria
* Known drug or alcohol abuse
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
* Participation in another study with an investigational drug within the 30 days preceding and during the present study
* Treatment with an injective approach in the previous 3 month
* Surgical treatment in the previous 12 months.
45 Years
80 Years
ALL
No
Sponsors
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Ente Ospedaliero Cantonale, Bellinzona
OTHER
Responsible Party
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Principal Investigators
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Christian Candrian, MD
Role: STUDY_CHAIR
EOC
Locations
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Christian Candrian
Lugano, , Switzerland
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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ORL-ORT-39
Identifier Type: -
Identifier Source: org_study_id
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