Resistance Training in Knee Osteoarthritis

NCT ID: NCT01099371

Last Updated: 2010-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-02-28

Study Completion Date

2011-02-28

Brief Summary

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The purpose of this study is to determine whether:

1. Progressive resistance training improves pain and disability
2. Progressive Resistance training improves muscular strength, ability to walk and quality of life

Detailed Description

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Patients in experimental group participated in a 12-week progressive resistance training using a repetition maximum (RM) exercise in which patients performed 1RM with the maximum bearable weight. Once the 1RM was determined, training was divided into the following regimen: 2 series of 8 repetitions, the first with 50% and the second with 70% of 1RM.

The exercises were knee extension and flexion and hip abduction and adduction, all performed in machines. The 1RM load was reevaluated every 2 weeks.

The control group remained on a three-month waiting list for physiotherapy. Patients were assessed for pain, function, quality of life, muscle strength and six-minute walk test.

Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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exercise

Group Type EXPERIMENTAL

exercise

Intervention Type OTHER

progressive resistance training

Interventions

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exercise

progressive resistance training

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Woman
* Age between 40-70 years old
* Pain between 3 and 8 on a 10-point numeric pain scale
* Radiographically confirmed knee OA

Exclusion Criteria

* Inflammatory diseases or any comorbidity that prohibit exercises, regular physical activity
* Trip plans for the next 12 months
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

Federal University of São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Federal University of Sao Paulo

Principal Investigators

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Jamil Natour, PhD

Role: STUDY_CHAIR

Federal University of São Paulo

Locations

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Federal University of Sao Paulo

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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FDAAAA

Identifier Type: -

Identifier Source: org_study_id

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