Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-03-31

Study Completion Date

2009-08-31

Brief Summary

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People with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training programs for these patients. This study objective was to compare the effectiveness of a supervised resistance muscular training (RT) versus sensorimotor training (SMT) for patients with Knee OA, on decrease of pain and functional improvement.

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Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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sensorimotor training (SMT)

Group Type ACTIVE_COMPARATOR

Sensorimotor training (SMT)

Intervention Type OTHER

The group realized 16 weeks of sensorimotor training, twice a week, with duration of 30 minutes each session. The intervention included agility and coordination exercises, perturbation training and stretching exercises. Also, the participants received orientation about the knee osteoarthritis.

Resistance training (RT)

Group Type ACTIVE_COMPARATOR

Resistance training (RT)

Intervention Type OTHER

The group realized 16 weeks of resistance training for the quadriceps and hamstring muscles, twice a week, with duration of 30 minutes each session. The intervention included strength leg raises, simple quadriceps and hamstring strengthening with cuff weights realized in 3 sets of ten repetition maximum(10RM) for each muscle group. The group also realized stretching exercises for lower limbs and received orientation about the knee osteoarthritis.

Control group (CG)

Group Type SHAM_COMPARATOR

Control group (CG)

Intervention Type OTHER

Patients in this group also received information about knee osteoarthritis and realized the same warm-up and cool-down intervention realized in the interventional groups. During 16 weeks they went to the ambulatory twice a week to perform 5 minutes of stationary bicycle and 5 minutes of stretching exercises for lower limbs.

Interventions

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Sensorimotor training (SMT)

The group realized 16 weeks of sensorimotor training, twice a week, with duration of 30 minutes each session. The intervention included agility and coordination exercises, perturbation training and stretching exercises. Also, the participants received orientation about the knee osteoarthritis.

Intervention Type OTHER

Resistance training (RT)

The group realized 16 weeks of resistance training for the quadriceps and hamstring muscles, twice a week, with duration of 30 minutes each session. The intervention included strength leg raises, simple quadriceps and hamstring strengthening with cuff weights realized in 3 sets of ten repetition maximum(10RM) for each muscle group. The group also realized stretching exercises for lower limbs and received orientation about the knee osteoarthritis.

Intervention Type OTHER

Control group (CG)

Patients in this group also received information about knee osteoarthritis and realized the same warm-up and cool-down intervention realized in the interventional groups. During 16 weeks they went to the ambulatory twice a week to perform 5 minutes of stationary bicycle and 5 minutes of stretching exercises for lower limbs.

Intervention Type OTHER

Other Intervention Names

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Agility/perturbation training; proprioceptive training; neuromuscular training

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with tibiofemoral osteoarthritis;
* Both genders;
* Age\> 50 years \<75 years;
* Completion of clinical and radiological criteria of the American College of Rheumatology (ACR) criteria for knee OA;
* No physical activity in the previous 3 months;
* Education level from the 4th grade of primary school.

Exclusion Criteria

* uncontrolled hypertension;
* decompensated diabetes mellitus;
* uncontrolled thyroid diseases;
* cardiorespiratory disease (ischemia, arrhythmia, chest pain, or exercise-induced bronchospasm), liver abnormalities;
* Patients with grade IV functional limitation that needed devices to walk(Kellgren-Lawrence radiographic classification);
* Patients in a period of sick leave by the INSS or any other related factor;
* Other rheumatic diseases.

Minimum Eligible Age

50 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Aline Basolli Gomiero

Physical Therapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Virginia FM Trevisani, MD, MS, PhD

Role: STUDY_DIRECTOR

Federal University of São Paulo and Santo Amaro University