Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-01

Study Completion Date

2025-06-30

Brief Summary

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This is a prospective randomized study to compare endoscopic combined intrarenal surgery and PCNL as modalities of treatment for staghorn stones. In terms of efficacy and safety

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Detailed Description

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This is a prospective randomized study to compare endoscopic combined intrarenal surgery and PCNL as modalities of treatment for staghorn stones. In terms of efficacy and safety The efficacy will be studied at stone-free rate While efficacy will be studied using DMSA scan pre- and post-procedures in addition to the safety of each procedure with regard to intra- and post-operative complications,.

Conditions

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Urinary Calculi

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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• Group I (PCNL group)

50 patients will undergo percutaneous nephrolithotomy (PCNL).

Group Type EXPERIMENTAL

Combined Intrarenal Surgery and percutaneous nephrolithotomy

Intervention Type PROCEDURE

A study was conducted to compare endoscopic combined intrarenal surgery and percutaneous nephrolithotomy as modalities of treatment for staghorn stones.

Group II (ECIRS group)

50 patients will undergo endoscopic combined intrarenal surgery (ECIRS).

Group Type EXPERIMENTAL

Combined Intrarenal Surgery and percutaneous nephrolithotomy

Intervention Type PROCEDURE

A study was conducted to compare endoscopic combined intrarenal surgery and percutaneous nephrolithotomy as modalities of treatment for staghorn stones.

Interventions

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Combined Intrarenal Surgery and percutaneous nephrolithotomy

A study was conducted to compare endoscopic combined intrarenal surgery and percutaneous nephrolithotomy as modalities of treatment for staghorn stones.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients are more than 18 and less than 65 years old.
* Patients with renal staghorn stones based on imaging modalities (stones occupying the renal pelvis and extending into at least 2 major calyces).

Exclusion Criteria

* Patients with renal insufficiency (serum creatinine \> 1.6 mg/dl)
* patients with active urinary tract infection.
* Patients with congenital renal anomalies.
* Morbid obesity (BMI \> 35 kg/m2).
* Pregnancy.
* Bleeding Coagulopathy.
* Skeletal deformity

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No