to Study the Role of Retrograde Intrarenal Surgery in Management of Renal Stones
NCT ID: NCT05648877
Last Updated: 2023-01-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
NA
77 participants
INTERVENTIONAL
2020-10-01
2023-04-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Ultra Mini Percutaneous Nephrolithotomy VS Stented Extracorporeal Shock Wave Lithotripsy for Stone Management
NCT05697341
Retrograde Saline Irrigation During Supine Mini Percutaneous Nephrolithotomy
NCT06879990
Preoperative Prediction of Flexible Ureteroscopy Outcome in the Treatment of Renal Calculi
NCT05857501
Flexible Mini Percutaneous Nephrolithotomy Vs Retrograde Intra-renal Surgery
NCT06249100
Effectiveness of Single Use Flexible Ureteroscopes in Treatment of Renal Stones
NCT04578795
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Although, minimally invasive treatment modalities have an excellent stone fragmentation rate, the clearance of stone fragments may not be immediate and can occur for any time after the intervention.
The European Association of Urology (EAU) guidelines, recommends PCNL for renal stones greater than 2 cm, and SWL is suggested primarily for stones less than 1 cm in size. Although SWL, RIRS and PCNL are all presented as treatment options for renal stones between, which application is a matter of preference.
The treatment modality selection of renal stones usually depends on stone-related factors (location, size, and composition), clinical factors (patient's comorbidities, patient's compliance, solitary kidney, and abnormal anatomy), and technical factors (equipment available for treatment, success rates, possible complications, invasiveness, the need for anesthetics, hospitalization times, and costs).
PCNL can achieve better results but is more invasive, is associated with greater morbidity and complications, and may be reserved for selected circumstances.
Stone clearance following kidney stone treatment is not well defined. For lower pole stones, Sener and colleagues compared RIRS with SWL and reported a stone-free rate of 52.3% with patients treated using RIRS one week after treatment. However after three months, the stone-free rate improved to 100%.
Ureteroscopic lithotripsy has been the most widely applied treatment for urinary tract stones, with high success and low complication rates. The holmium laser has facilitated the disintegration of stones and increased the effectiveness of ureteroscopic lithotripsy.
Improvements in the new generation of flexible ureteroscopes have made retrograde endoscopic ureteroscopy and laser lithotripsy for renal calculi more popular. The overall success rates of retrograde intrarenal surgery have been reported as 75% to 95% for intrarenal stones \> 2 cm after the first or second treatment, whereas the major and minor complication rates vary from 1.5% to 12%, which are less frequent than rates in PCNL procedures.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
43 semirigid ureteropyeloscopy
43 Patients underwent semirigid ureteropyeloscopy
Ureteroscope
Role Of Retrograde Intrarenal Surgery In Management Of Renal Stones: Single Center Experience
34 flexible ureteropyeloscopy
34 patients with flexible ureteropyeloscopy
Ureteroscope
Role Of Retrograde Intrarenal Surgery In Management Of Renal Stones: Single Center Experience
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Ureteroscope
Role Of Retrograde Intrarenal Surgery In Management Of Renal Stones: Single Center Experience
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Menoufia University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Mohammed Ali abdelghaffar
Menoufia gevernorate
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Menoufia faculty of medicine
Shibīn al Kawm, Monufia Governorate, Egypt
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
11/2020 urol
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.