Outcome of URS in Fresh Versus Recurrent Cases of Stone Ureter

NCT ID: NCT06592469

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-01

Study Completion Date

2025-11-30

Brief Summary

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Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter

Detailed Description

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Urolithiasis is a common cause of both urology outpatient clinic and emergency room encounters. Approximately 75-90% of ureteral stones pass spontaneously. from this point of view other managements of ureteric stones either ESWL, ureteroscopy or open surgery according to location, site, size, and density. Ureteroscopy is commonly used to diagnose and treat kidney and ureteral stones, ureteral strictures, and urothelial cancers. Semirigid URS is the gold standard of treatment for ureteral stones. High success rates and low morbidity have been reported in semirigid URS. but complications still occur in some cases. The possibility to predict their occurrence should influence patient advisement and better case selection. there are many predictors of successful URS as age, gender, previous ESWL, and stone character. In addition, the impacted stone is a risk factor, and it is described in the literature as ureteral wall thickness, higher grades of hydronephrosis, ureteral stricture, polyp, inflammatory reaction, and difficulty to introduce the guide wire. the literature is very poor in illustrating the previous procedures as a predictor of successful URS only seen in very few original articles as second-time URS after any procedure decreases the rate of success, so it is a point of research that Amr Moustafa aims to clarify. Amr Moustafa will conduct a prospective study to evaluate the outcomes of URS for stones in the fresh and recurrent cases.

Conditions

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Stone Ureter

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Fresh cases

Outcome of URS in fresh stone ureter

Ureteroscopy

Intervention Type PROCEDURE

URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Recurrent cases

Outcome of URS in recurrent cases of stone ureter post ESWL ,URS , open surgery

Ureteroscopy

Intervention Type PROCEDURE

URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Interventions

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Ureteroscopy

URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Intervention Type PROCEDURE

Other Intervention Names

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URS

Eligibility Criteria

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Inclusion Criteria

* • all cases with middle and lower ureteric stone candidate for endoscopy.

* Stone 15mm or less.

Exclusion Criteria

* • Patients with a ureteral stent.

* Patient refusing participation.
* Pregnant woman.
* Active urinary tract infection.
* Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Amr Moustafa Hussein Soliman

Resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fathy Gaber Mahmoud Alanany, Prof of URO

Role: STUDY_DIRECTOR

Assiut University

Mahmoud M. Shalaby, Prof of URO

Role: STUDY_DIRECTOR

Assiut University

Nasreldin Abdeal Mohammed, Ass Prof

Role: STUDY_DIRECTOR

Assiut University

Locations

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Faculty of Medicine Assiut University

Asyut, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Amr Moustafa Hussein Soliman, Resident dr

Role: CONTACT

+201140340697

Related Links

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https://pubmed.ncbi.nlm.nih.gov/33818430/

Factors predicting duration and success of semirigid ureteroscopy for ureteral stones in different localizations

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060607/

Assessment of factors affecting the spontaneous passage of lower ureteric calculus on the basis of lower ureteric calculus diameter, density, and plasma C-reactive protein level. Urology Annal

https://pubmed.ncbi.nlm.nih.gov/30719571/

Stone composition independently predicts stone size in 18,029 spontaneously passed stones

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103480/

Outcomes of Shock Wave Lithotripsy and Ureteroscopy for Treatment of Pediatric Urolithiasis

https://pubmed.ncbi.nlm.nih.gov/24890883/

Pushing the boundaries of ureteroscopy: current status and future perspectives

https://pubmed.ncbi.nlm.nih.gov/32459149/

Semirigid Ureteroscopy: Step by Step

https://pubmed.ncbi.nlm.nih.gov/15735383/

Complications of pneumatic ureterolithotripsy in the early postoperative period

https://pubmed.ncbi.nlm.nih.gov/16548724/

Complications of 2735 retrograde semirigid ureteroscopy procedures: a single-center experience

https://pubmed.ncbi.nlm.nih.gov/14665851/

Endoscopic features of impacted ureteral stones

https://pubmed.ncbi.nlm.nih.gov/18632141/

Predictive factors for intraoperative complications in semirigid ureteroscopy: analysis of 1235 ballistic ureterolithotripsies

https://pubmed.ncbi.nlm.nih.gov/22641488/

Revisiting the predictive factors for intra-operative complications of rigid ureteroscopy: a 15-year experience

Other Identifiers

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Outcome of Ureteroscopy

Identifier Type: -

Identifier Source: org_study_id

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