Multitract Percutaneous Nephrolithotomy(PCNL) in Large Renal Stones.

NCT ID: NCT05291702

Last Updated: 2022-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-01

Study Completion Date

2024-10-01

Brief Summary

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Investigator aimed to analyze the clinical efficacy and safety of multiple tracts PCNL as one step therapy to treat the staghorn stones or multiple calyceal calculi which are inaccessible by single tract

Detailed Description

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Staghorn calculi are branched stones either partial or complete occupying the pelvis and one or more of the renal caliceal system that is detected by non contrast computrized tomography (NCCT) and plain on kidney, ureter, urinary bladder (KUB). An untreated staghorn calculus over time can damage the kidney and deteriorate its function and /or cause life threatening sepsis.

Total stone clearance is an important goal to eradicate any infective focus, relieve obstruction and preserve the kidney function.

Based on American Urological Association (AUA) guideline, PCNL is the most effective, safest and minimally invasive treatment option compared to open surgery

Conditions

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Staghorn Calculi

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Multitract PCNL patients

Assessment of the multitract PCNL procedure in removal of large renal stones using pneumatic or laser lithotripsy.

Group Type OTHER

PCNL

Intervention Type PROCEDURE

Percutaneous nephrolithotomy ( Extraction of the renal stones using the nephroscope/ Ureteroscope )

Interventions

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PCNL

Percutaneous nephrolithotomy ( Extraction of the renal stones using the nephroscope/ Ureteroscope )

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Adult patients more than 18 years old.
2. Patients with staghorn stone (partial, complete).
3. Patients with multiple calyceal calculi which are inaccessible by single tract.

Exclusion Criteria

1. Patients under 18 years old.
2. Patients with renal anomalies.
3. Patients with only function kidney.
4. Patients with distal ureteric obstruction.
5. Patients with radiolucent stone.
6. Patients with febrile urinary tract infection.
7. Patients with abnormal coagulopathy state.
8. Patients refused to participate in this study.
9. pregnancy.
10. Musculoskeletal deformity.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Waleed Mahmoud Ali Abbas

Principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Waleed Mahmoud Abbas, M.Sc

Role: CONTACT

+2001009377858

Mohamed Ali Zarzour, MD

Role: CONTACT

+2001014714142

References

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Romero V, Akpinar H, Assimos DG. Kidney stones: a global picture of prevalence, incidence, and associated risk factors. Rev Urol. 2010 Spring;12(2-3):e86-96.

Reference Type BACKGROUND
PMID: 20811557 (View on PubMed)

Turk C, Petrik A, Sarica K, et al. Urolithiassis. European Association of Urolgy. Accessed: August 23,2019.

Reference Type BACKGROUND

Assimos D, Krambeck A, Miller NL, Monga M, Murad MH, Nelson CP, Pace KT, Pais VM Jr, Pearle MS, Preminger GM, Razvi H, Shah O, Matlaga BR. Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I. J Urol. 2016 Oct;196(4):1153-60. doi: 10.1016/j.juro.2016.05.090. Epub 2016 May 27.

Reference Type BACKGROUND
PMID: 27238616 (View on PubMed)

Zhu W, Liu Y, Liu L, Lei M, Yuan J, Wan SP, Zeng G. Minimally invasive versus standard percutaneous nephrolithotomy: a meta-analysis. Urolithiasis. 2015 Nov;43(6):563-70. doi: 10.1007/s00240-015-0808-y. Epub 2015 Aug 5.

Reference Type BACKGROUND
PMID: 26242465 (View on PubMed)

Other Identifiers

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Multitract PCNL

Identifier Type: -

Identifier Source: org_study_id

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