Correlation Analysis of POD and pNCD in Elderly Spinal Surgery Patients
NCT ID: NCT06466083
Last Updated: 2025-04-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
165 participants
OBSERVATIONAL
2025-01-14
2026-07-01
Brief Summary
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Detailed Description
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Neurocognitive function of the study participants was assessed within one week before surgery using the Montreal Cognitive Assessment (MoCA). Compare changes in serum indexes level before and after surgery. Under routine anesthetic management of the Department of Anesthesiology and Surgical Operations at Xuanwu Hospital, endotracheal intubation general anesthesia was performed. Within 7 days post-surgery, delirium assessment was conducted using the Confusion Assessment Method (CAM), classifying patients into POD and non-POD groups. Neurocognitive function assessments were conducted long-term after surgery for the POD group to determine the presence of pNCD, further dividing the POD group into pNCD and non-pNCD subgroups, followed by serum indexes.By comparing the changes of serum indexes before and after surgery between the pNCD and non-pNCD subgroups, exploring the correlation of POD and pNCD.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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postoperative delirium(POD) and postoperative neurocognitive disorder(pNCD)
Delirium (CAM scale ) was assessed 7 days after surgery and divided into POD and non-POD groups; one of the above scenarios indicated postoperative delirium;The patients in the POD group were evaluated for cognitive function at 1 month and 12 months after surgery to determine whether pNCD occurred. The patients in the POD group were further divided into pNCD subgroup and non-PNCD subgroup, and serum indexes were compared
no intervention
this is an observation study,no intervention
Interventions
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no intervention
this is an observation study,no intervention
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
65 Years
100 Years
ALL
No
Sponsors
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Xuanwu Hospital, Beijing
OTHER
Responsible Party
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Locations
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Xuanwu Hospital, Capital Medical University, Beijing, 100053
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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19880416
Identifier Type: -
Identifier Source: org_study_id
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